| Disentangle after a tackle | 26 |
| Disentangle | 11 |
| Disengages, as from a habit | 27 |
| Disengages, as a clutch | 23 |
| Disengages from a habit | 23 |
| Disengages | 10 |
| Disengaged: Abbr. | 17 |
| Disengaged, as an engine | 24 |
| Disengaged | 10 |
| Disengage? | 10 |
| Disengage, in a way | 19 |
| Disengage | 9 |
| Disenfranchised slackers, supposedly | 36 |
| Disencumbers | 12 |
| Disencumbered (of) | 18 |
| Disencumbered | 13 |
| Disencumber (with ''of'') | 41 |
| Disencumber (of) | 16 |
| Disencumber | 11 |
| Disenchanted fan, at times | 26 |
| Disenchanted fan | 16 |
| Disenchanted | 12 |
| Disen-cumbers | 13 |
| Disemploy | 9 |
| Disembowel | 10 |
| Disembogues | 11 |
| Disembogue | 10 |
| Disembodied spirits | 19 |
| Disembodied souls, in Judaism | 29 |
| Disembodied sci-fi antagonist | 29 |
| Disembodied brain allied with Shredder | 38 |
| Disembarrasses | 14 |
| Disembarrass (with "of") | 34 |
| Disembarrass (with ''of'') | 42 |
| Disembarrass (of) | 17 |
| Disembarrass | 12 |
| Disembarks, at Dulles | 21 |
| Disembarks from | 15 |
| Disembarks | 10 |
| Disembarking spots | 18 |
| Disembarking site | 17 |
| Disembarked from a jet | 22 |
| Disembarked | 11 |
| Disembarkation site | 19 |
| Disembark, in a way | 19 |
| Disembark at O'Hare | 23 |
| Disembark | 9 |
| Diseases of rye | 15 |
| Diseases of ramblers | 20 |
| Diseases of grapevines | 22 |
| Diseased Subhumans song? | 24 |
| Diseased parts of wood | 22 |
| Diseased | 8 |
| Disease: Suffix | 15 |
| Disease-struck tree | 19 |
| Disease-stricken tree | 21 |
| Disease-free sea predators? | 27 |
| Disease-fighting protein | 24 |
| Disease-causing microorganism | 29 |
| Disease-causing bacteria | 24 |
| Disease-carrying mosquito | 25 |
| Disease-carrying insect | 23 |
| Disease-carrying flies | 22 |
| Disease, in combos | 18 |
| Disease with muscular spasms | 28 |
| Disease whose name is a reduplication of the Sinhalese word for "weakness" | 84 |
| Disease tsetses cause | 21 |
| Disease treated with tretinoin | 30 |
| Disease transmitted by mosquitoes | 33 |
| Disease that seems to occur only at the Edward Scissorhands dairy? | 66 |
| Disease that makes you say "aww" all the time? | 56 |
| Disease that killed Freddie Mercury | 35 |
| Disease that killed David Niven: Abbr. | 38 |
| Disease that David Niven had, for short | 39 |
| Disease that comes in types A, B, and C, most commonly | 54 |
| Disease spread by tsetse flies | 30 |
| Disease spread by mosquitoes | 28 |
| Disease spread by IV drug use, briefly | 38 |
| Disease sources | 15 |
| Disease research org. | 21 |
| Disease preventives | 19 |
| Disease popular in comic strips | 31 |
| Disease one gets from a watering hole? | 38 |
| Disease of the East | 19 |
| Disease of sweet potatoes | 25 |
| Disease of sheep | 16 |
| Disease of rye | 14 |
| Disease of plants | 17 |
| Disease of overripe fruit | 25 |
| Disease of livestock | 20 |
| Disease of fishes | 17 |
| Disease of domestic animals | 27 |
| Disease of dogs | 15 |
| Disease of cereals | 18 |
| Disease of cereal grasses | 25 |
| Disease of apple and pear trees | 31 |
| Disease named after a Congolese river | 37 |
| Disease germ | 12 |
| Disease generally vaccinated against with measles and rubella | 61 |
| Disease from living with too many scantily-clad wives? | 54 |