| ___ odds on | 11 |
| ___ odds (antagonize) | 21 |
| ___ odds (alienate) | 19 |
| ___ oculi (muscle of the eye) | 29 |
| ___ Octubre (nickname of Orlando Hernández after he went 8-0 to start his postseason career) | 95 |
| ___ Octavius (Spider-Man villain) | 33 |
| ___ Octavius ("Spider-Man" villain Doc Ock's "real" name) | 81 |
| ___ Octavius ("Spider Man" villain) | 45 |
| ___ Ocean, Julia Roberts's "Ocean's Eleven" role | 66 |
| ___ occasions (seldom) | 22 |
| ___ occasion (never) | 20 |
| ___ occasion | 12 |
| ___ obstat (error-free) | 23 |
| ___ obstante | 12 |
| ___ Observatory, home of the world's largest single-aperture radio telescope | 80 |
| ___ Observatory | 15 |
| ___ obscure (chiaroscuro) | 25 |
| ___ oblongata (brain part) | 26 |
| ___ oblige | 10 |
| ___ Obispo | 10 |
| ___ Obama (novelty gift) | 24 |
| ___ Obama (controversial kitsch item) | 37 |
| ___ oats (cereal ingredient) | 28 |
| ___ oak | 7 |
| ___ O'Shea, music-hall star | 31 |
| ___ o'Shanter | 17 |
| ___ O's (Post cereal) | 25 |
| ___ O's (chocolaty cereal) | 30 |
| ___ O'Neill Chaplin | 23 |
| ___ O'Neill | 15 |
| ___ O'More, name of three Irish chieftains | 46 |
| ___ O'Hara, Bill Bixby's role on "My Favorite Martian" | 72 |
| ___ o'clock scholar | 23 |
| ___ o' Shanter | 18 |
| ___ o' livin' | 21 |
| ___ o menos (basically, in Spanish) | 35 |
| ___ nutshell (succinctly) | 25 |
| ___ nutshell | 12 |
| ___ nut (wheel fastener) | 24 |
| ___ nut (narcotic Asian leaf) | 29 |
| ___ nut (caffeine source) | 25 |
| ___ nut | 7 |
| ___ Nurmi, the Flying Finn | 26 |
| ___ Nurmi, nine-time track gold medalist in 1920s Olympics | 58 |
| ___ Nung, legendary Chinese emperor | 35 |
| ___ number on (unnerve) | 23 |
| ___ number on (treats badly) | 28 |
| ___ number on (psyched out) | 27 |
| ___ number on (mess up) | 23 |
| ___ number on (mentally abuses) | 31 |
| ___ number on | 13 |
| ___ number (speed ratio) | 24 |
| ___ number (speed measure) | 26 |
| ___ number (set theory concept) | 31 |
| ___ number (proton count) | 25 |
| ___ number (ID on all stocks and registered bonds) | 50 |
| ___ number (gasoline rating) | 28 |
| ___ number | 10 |
| ___ nullius (no man's land) | 31 |
| ___ null (set theory concept) | 29 |
| ___ nuit (tonight, in Tours) | 28 |
| ___ nuit | 8 |
| ___ Nui (Easter Island) | 23 |
| ___ Nui | 7 |
| ___ nuff! | 9 |
| ___ Nuevo (Spanish New Year) | 28 |
| ___ nuevo | 9 |
| ___ Nublar ("Jurassic Park") locale | 45 |
| ___ Nublar ("Jurassic Park" setting) | 46 |
| ___ Nublar ("Jurassic Park" location) | 47 |
| ___ Nubbles, Dickens lad | 24 |
| ___ nth degree | 14 |
| ___ now! (immediately!) | 23 |
| ___ now and then | 16 |
| ___ now and again | 17 |
| ___ now (today) | 15 |
| ___ now (to this point) | 23 |
| ___ now (to date) | 17 |
| ___ now (so far) | 16 |
| ___ now (presently) | 19 |
| ___ now (immediately) | 21 |
| ___ now (currently) | 19 |
| ___ now (at this time) | 22 |
| ___ now | 7 |
| ___ Novotny, 1950's-60's Czech president | 48 |
| ___ Novo, Dahomey's capital | 31 |
| ___ Novo (Benin's capital) | 30 |
| ___ Novo (Benin capital) | 24 |
| ___ Novello Award for songwriters | 33 |
| ___ novel | 9 |
| ___ Novák, Czech critic | 26 |
| ___ novarum | 11 |
| ___ Novarro, 1926 Ben Hur | 25 |
| ___ nova, music style | 21 |
| ___ nova, dance meaning "new bump" | 44 |
| ___ nova, Brazilian dance | 25 |
| ___ nova (samba music) | 22 |
| ___ Nova (music style) | 22 |
| ___ nova (Brazilian music) | 26 |
| ___ nova (Brazilian dance) | 26 |