| Female saints | 13 |
| Female saint: Lat. | 18 |
| Female saint: French abbr. | 26 |
| Female Saint, for short | 23 |
| Female saint, abbr. | 19 |
| Female ruminants | 16 |
| Female ruminant | 15 |
| Female ruffs | 12 |
| Female ruff | 11 |
| Female royalty | 14 |
| Female role in "Chicago" | 34 |
| Female rocker with the 2003 hit "Why Can't I?" | 60 |
| Female reunion attendees | 24 |
| Female reproductive gland | 25 |
| Female reproductive cells | 25 |
| Female relatives | 16 |
| Female relative | 15 |
| Female relations | 16 |
| Female rel. | 11 |
| Female red deer | 15 |
| Female rat | 10 |
| Female rapper ___ Digga | 23 |
| Female rapper with the 2002 hit "Gangsta Lovin'" | 62 |
| Female rap trio with the #1 hit "Waterfalls" | 54 |
| Female Rambouillet, say | 23 |
| Female rake? | 12 |
| Female rabbits | 14 |
| Female rabbit or deer | 21 |
| Female rabbit | 13 |
| Female pub employee | 19 |
| Female protagonists | 19 |
| Female prophets | 15 |
| Female prophet | 14 |
| Female pronoun | 14 |
| Female prison official | 22 |
| Female precursor to vampires | 28 |
| Female power principle, in Hinduism | 35 |
| Female porkers | 14 |
| Female pop trio since 1979 | 26 |
| Female political refugee | 24 |
| Female poet known to friends as "Vincent" | 51 |
| Female player | 13 |
| Female pigs | 11 |
| Female pig | 10 |
| Female pheasants | 16 |
| Female pheasant | 15 |
| Female persons | 14 |
| Female peckers | 14 |
| Female patron saint of Ireland | 30 |
| Female part of a flower | 23 |
| Female parents, for short | 25 |
| Female parents | 14 |
| Female parent's annoyance? | 30 |
| Female parent | 13 |
| Female padre? | 13 |
| Female ovines | 13 |
| Female ovine | 12 |
| Female organizations | 20 |
| Female oracles | 14 |
| Female oracle | 13 |
| Female opera villain, often | 27 |
| Female opera stars | 18 |
| Female opera star | 17 |
| Female opera singer | 19 |
| Female Olympian | 15 |
| Female of the ruff | 18 |
| Female of the forest | 20 |
| Female of the ball | 18 |
| Female octopus | 14 |
| Female octopi | 13 |
| Female novelist whose real first name was Howard | 48 |
| Female ninja and love interest of Daredevil | 43 |
| Female New World sheep? | 23 |
| Female New Testament disciple | 29 |
| Female NASCAR racer/eco-activist ___ Munter | 43 |
| Female name suffix | 18 |
| Female name ending | 18 |
| Female nags | 11 |
| Female motorcyclists, in biker slang | 36 |
| Female mosquito | 15 |
| Female monster of Greek myth | 28 |
| Female monster | 14 |
| Female monarca | 14 |
| Female military gp. | 19 |
| Female mil. unit created 5/15/42 | 32 |
| Female metal singer Shamaya | 27 |
| Female member of the bar? | 25 |
| Female member of a moving company? | 34 |
| Female megastar, in pop music | 29 |
| Female megastar, in music | 25 |
| Female massager | 15 |
| Female lobsters | 15 |
| Female lobster, e.g. | 20 |
| Female lobster | 14 |
| Female lion's lack | 22 |
| Female leopard or puma | 22 |
| Female lead on "Frasier" | 34 |
| Female lead in "Brigadoon" | 36 |
| Female lagomorph | 16 |
| Female lab assistant who went for a "roll in the hay" in "Young Frankenstein" | 97 |