| Fictional friend of a runaway slave | 35 |
| Fictional Friday slugabed | 25 |
| Fictional friar | 15 |
| Fictional Frenchman | 19 |
| Fictional free-spirited aunt | 28 |
| Fictional Fort Baxter noncom | 28 |
| Fictional Forrest | 17 |
| Fictional flower girl Doolittle | 31 |
| Fictional flies' leader | 27 |
| Fictional fliers | 16 |
| Fictional flier | 15 |
| Fictional flapper | 17 |
| Fictional Flanders and Plimpton | 31 |
| Fictional Flanders and Devine | 29 |
| Fictional Flanders | 18 |
| Fictional Finn | 14 |
| Fictional fiends | 16 |
| Fictional fiend | 15 |
| Fictional feline | 16 |
| Fictional FBI agent Scully | 26 |
| Fictional Faulkner clan | 23 |
| Fictional father of octuplets | 29 |
| Fictional farmer Frome | 22 |
| Fictional fantasizer | 20 |
| Fictional family traveling west | 31 |
| Fictional falcon's home | 27 |
| Fictional falcon source | 23 |
| Fictional falcon seeker | 23 |
| Fictional falcon hunter | 23 |
| Fictional falcon finder | 23 |
| Fictional faithful friend | 25 |
| Fictional explorer who also plays the flute | 43 |
| Fictional expatriate | 20 |
| Fictional estate near Atlanta | 29 |
| Fictional estate | 16 |
| Fictional English detective | 27 |
| Fictional elocution student | 27 |
| Fictional elephant who debuted in 1931 | 38 |
| Fictional elephant king | 23 |
| Fictional elephant | 18 |
| Fictional Edwin | 15 |
| Fictional editor in chief White | 31 |
| Fictional dwarf | 15 |
| Fictional duo | 13 |
| Fictional Drood | 15 |
| Fictional dreamer | 17 |
| Fictional Doone | 15 |
| Fictional Doolittle | 19 |
| Fictional donkey | 16 |
| Fictional dog from Kansas | 25 |
| Fictional dog | 13 |
| Fictional doctor played by Neil Patrick Harris | 46 |
| Fictional doctor | 16 |
| Fictional diva Floria | 21 |
| Fictional Dinsmore and Venner | 29 |
| Fictional Dinsmore | 18 |
| Fictional dieter Jack | 21 |
| Fictional Dick | 14 |
| Fictional diary writer | 22 |
| Fictional diarist Bridget | 25 |
| Fictional detective ___ Pym | 27 |
| Fictional detective ___ Archer | 30 |
| Fictional detective Wolfe | 25 |
| Fictional detective who's a board member? | 45 |
| Fictional detective who weighs a seventh of a ton | 49 |
| Fictional detective Vance | 25 |
| Fictional detective Spade | 25 |
| Fictional detective skilled in judo | 35 |
| Fictional detective Philip | 26 |
| Fictional detective Lupin | 25 |
| Fictional detective Charlie | 27 |
| Fictional detective and gourmand Wolfe | 38 |
| Fictional detective and cruciverbalist who attended Oxford | 58 |
| Fictional detective | 19 |
| Fictional destroyer of Tokyo | 28 |
| Fictional Della | 15 |
| Fictional deli of Phoenix | 25 |
| Fictional defense attorney | 26 |
| Fictional deer | 14 |
| Fictional daydreamer | 20 |
| Fictional daddy | 15 |
| Fictional critter known for its grin | 36 |
| Fictional criminal Lupin | 24 |
| Fictional criminal genius | 25 |
| Fictional crime-fighting attire | 31 |
| Fictional crime family name | 27 |
| Fictional crime family | 22 |
| Fictional creature whose name is Old English for "giant" | 66 |
| Fictional creature that "always looks grave at a pun" | 63 |
| Fictional creature born of a post-midnight feeding | 50 |
| Fictional coward | 16 |
| Fictional cousin known as "TÃo Cosa" in Latin America | 66 |
| Fictional courage seeker | 24 |
| Fictional Cossack ___ Bulba | 27 |
| Fictional corporation that supplied rocket-powered roller skates and jet-propelled pogo sticks | 94 |
| Fictional corporation that sells earthquake pills and portable holes | 68 |
| Fictional Copperfield | 21 |
| Fictional Connecticut robot town | 32 |
| Fictional computer with cognitive circuits | 42 |
| Fictional composer P.D.Q. ___ | 29 |