| Special-handling designation at the post office | 47 |
| Special-request flight meal option | 34 |
| Specialist for cooks who are kooks? | 35 |
| Specialist in the study of nutrition | 36 |
| Specialist who delivers for the Sopranos? | 41 |
| Specialist who keeps a Kardashian healthy? | 42 |
| Specialist who listens to sole music? | 37 |
| Specialist who might conduct a balance test | 43 |
| Specialist who might treat otitis interna | 41 |
| Specialist who treats Santa's broken ankle? | 47 |
| Specialist whose field covers 675,000 species | 45 |
| Specialist's offering, in court | 35 |
| Specialist's superior: Abbr. | 32 |
| Specialists' underlings: Abbr. | 34 |
| Specialized "We made it!" | 35 |
| Specialized procedures, so to speak | 35 |
| Specially created, as a committee | 33 |
| Specially edited version of a film | 34 |
| Specially formed, as a committee | 32 |
| Specialties at Wilhelm's fruit stand? | 41 |
| Specialties of tonsorial artists | 32 |
| Specialty for Jose Reyes of the Mets | 36 |
| Specialty for some thoroughbreds | 32 |
| Specialty in history as well as medicine? | 41 |
| Specialty of a couples therapist? | 33 |
| Specialty of a Library of Congress | 34 |
| Specialty of an M.D. who deals with head cases? | 47 |
| Specialty of certain "deliverymen" | 44 |
| Specialty of Edward Scissorhands | 32 |
| Specialty of Robert McG. Thomas Jr. | 35 |
| Specialty of Russian painter Aivazovsky | 39 |
| Specialty of the funny Avon lady? | 33 |
| Specialty retailers' domains | 32 |
| Specialty sandwich from Domino's? | 37 |
| Specialty that involves the brain and spinal cord | 49 |
| Species of falcon also called an American kestrel | 49 |
| Species of Tolkien's Arwen Evenstar | 39 |
| Species that serves as an early warning system | 46 |
| Specific item in a sleepwear collection? | 40 |
| Specification in the ketchup aisle | 34 |
| Specification to a butcher, perhaps | 35 |
| Specification with a steak order | 32 |
| Specifications marked on 10-hole harmonicas | 43 |
| Specifies one's cohorts in crime | 36 |
| Specimen in a simian autopsy, maybe? | 36 |
| Specious hangover "cure" | 34 |
| Speck in a magnetic field experiment | 36 |
| Specks of light in some home movies, purportedly | 48 |
| Spectacle depicted in many Picasso paintings | 44 |
| Spectacle in Philadelphia on Jan. 1 | 35 |
| Spectacled bo's'n of fiction | 36 |
| Spectator orchestra in the works | 32 |
| Spectators' cries of disapproval | 36 |
| Specter coming around to your way of thinking? | 46 |
| Specter seen in the Capitol building | 36 |
| Specter that appears twenty-four times a day? | 45 |
| Spector, of "Wall of Sound" fame | 42 |
| Spectrum color between blue and violet | 38 |
| Speculate, as with borrowed funds | 33 |
| Speculative stock, or Dracula when hopped-up? | 45 |
| Speech at a major high school dance? | 36 |
| Speech center of the brain, ___'s area | 42 |
| Speech that leads to some soul-searching | 40 |
| Speed at which the apocalypse is coming? | 40 |
| Speed at which the shell game could be played? | 46 |
| Speed away (with ''out'') | 41 |
| Speed away, with "out" | 32 |
| Speed letters "trapped" in this puzzle | 48 |
| Speed measuring instrument (Abbr.) | 34 |
| Speed of rotation measurer, briefly | 35 |
| Speed skater Apolo Anton Ohno's specialty | 45 |
| Speed skating medalist Lemay ______ | 36 |
| Speed unit in telecommunications | 32 |
| Speed ___ (traffic-calming device) | 34 |
| Speed's mysterious nemesis, in cartoons | 43 |
| Speed-skating champ Johann ___ Koss | 35 |
| Speed-skating champion Gustafson | 32 |
| Speed-skating gold medalist Jansen | 34 |
| Speed-skating gold medalist Karin | 33 |
| Speeder catchers in the Sunshine State: abbr. | 45 |
| Speeder's metaphorical feature | 34 |
| Speeding car on a sharp turn, e.g. | 34 |
| Speedometer's lowest reading | 32 |
| Speedster in "The Incredibles" | 40 |
| Speedy "Guys and Dolls" author? | 41 |
| Speedy base runner's strategy | 33 |
| Speedy Boston-to-Washington transport | 37 |
| Speedy Boston-Washington connection | 35 |
| Speedy breed of steed, for short | 32 |
| Speedy Buttons runs down acid dye | 33 |
| Speedy Washington-Boston connection | 35 |
| Speedy Washington-to-Boston link | 32 |
| Spell that's cast retroactively? | 36 |
| Speller's words of clarification | 36 |
| Spellin' things incorrectly? | 32 |
| Spelling of Beverly Hills 90210 | 35 |
| Spelling bee contestant request #1 | 34 |
| Spelling bee contestant request #2 | 34 |
| Spelling bee contestant request #3 | 34 |
| Spelling bee contestant request #4 | 34 |