| Detroit suburb __ Pointe | 24 |
| Detroit team in first place | 27 |
| Detroit Tigers great Al | 23 |
| Detroit union, for short | 24 |
| Detroit's Cobo Hall | 23 |
| Detroit's famed hall | 24 |
| Detroit's first name | 24 |
| Detroit's Franklin | 22 |
| Detroit's Joe Louis ___ | 27 |
| Detroit's Joe Louis, e.g. | 29 |
| Detroit's locale: Abbr. | 27 |
| Detroit's __ Arena | 22 |
| Detroit's ___ Arena | 23 |
| Detroit's ___ Center | 24 |
| Detroit's ___ Louis Arena | 29 |
| Detroit, for the records | 24 |
| Detroit-based finance co. | 25 |
| Detroit-based financial org. | 28 |
| Detroit-based labor gp. | 23 |
| Detroit-based labor org. | 24 |
| Detroit-based union: Abbr. | 26 |
| Detroit-to-Atlanta dir. | 23 |
| Detroit-to-Baton Rouge dir. | 27 |
| Detroit-to-Montreal dir. | 24 |
| Detroit-to-Nashville dir. | 25 |
| Detroit-to-Philadelphia dir. | 28 |
| Detroit-to-Toronto dir. | 23 |
| Detroiter's neighbor | 24 |
| Detrol prescriber's field | 29 |
| Deuce and a half deuce | 22 |
| Deuce and a half-deuce | 22 |
| Deuce beaters, in cards | 23 |
| Deuce follower in tennis | 24 |
| Deuce follower, at times | 24 |
| Deuce follower, in cards | 24 |
| Deuce follower, in tennis | 25 |
| Deuce follower, sometimes | 25 |
| Deuce or trey, for example | 26 |
| Deuce or trey, so to speak | 26 |
| Deuce topper, in cards | 22 |
| Deuterium discoverer Harold | 27 |
| Deuterium is an isotope of it | 29 |
| Deuterium ___ (heavy water) | 27 |
| Deuterium's discoverer | 26 |
| Deutsche Telekom subsidiary | 27 |
| Deutschland "de" | 26 |
| Deutschland coal section | 24 |
| Deux-quatre go-between | 22 |
| Deuxieme ___ (the nobility) | 27 |
| Devalue for a collector | 23 |
| Devastated by fighting | 22 |
| Devastating 2008 hurricane | 26 |
| Devastating damage doer | 23 |
| Devastating hurricane of 1972 | 29 |
| Develop an itch, as it were | 27 |
| Develop à la Darwin | 22 |
| Develop by gradual changes | 26 |
| Develop flavor, perhaps | 23 |
| Develop in a particular way | 27 |
| Develop slowly, as an idea | 26 |
| Develop stage fright, say | 25 |
| Develop thick skin (var.) | 25 |
| Develop ___ of the jitters | 26 |
| Develop, as an opinion | 22 |
| Developed a fondness for | 24 |
| Developed a liking for | 22 |
| Developed germs, maybe | 22 |
| Developed motion-picture film | 29 |
| Developed, as a player | 22 |
| Developer of I.Q. tests | 23 |
| Developer of polio vaccine | 26 |
| Developer's concern | 23 |
| Developer's deliveries? | 27 |
| Developer's divisions | 25 |
| Developer's drawing | 23 |
| Developer's graphics | 24 |
| Developer's interest | 24 |
| Developer's inventory | 25 |
| Developer's investment | 26 |
| Developer's land unit | 25 |
| Developer's measure | 23 |
| Developer's offering | 24 |
| Developer's offerings | 25 |
| Developer's purchase | 24 |
| Developer's reference | 25 |
| Developers' acquisitions | 28 |
| Developers' concerns | 24 |
| Developers' expanses | 24 |
| Developers' interests | 25 |
| Developers' purchases | 25 |
| Developing an attachment? | 25 |
| Developing chain of old | 23 |
| Developing country's need | 29 |
| Developing fetus, slangily | 26 |
| Developing little by little | 27 |
| Developing option: Abbr. | 24 |
| Developing, as a skill | 22 |
| Development developments | 24 |
| Development of amnesia? | 23 |
| Development of an organism | 26 |