| Centers of learning in the Dark Ages | 36 |
| Centers of interest | 19 |
| Centers of intellectual activity | 32 |
| Centers of hurricanes | 21 |
| Centers of great activity | 25 |
| Centers of early development | 28 |
| Centers of countries | 20 |
| Centers of circles | 18 |
| Centers of Christmas wrapping paper | 35 |
| Centers of cherries | 19 |
| Centers of cells | 16 |
| Centers of casino action | 24 |
| Centers of attraction | 21 |
| Centers of attention? | 21 |
| Centers of attention | 20 |
| Centers of aggression | 21 |
| Centers of activity | 19 |
| Centers of action | 17 |
| Centers for G.I.'s | 22 |
| Centers for fem. advocacy | 25 |
| Centers for dissenters | 22 |
| Centers for Disease Control headquarters site | 45 |
| Centers and tackles | 19 |
| Centers and guards, e.g. | 24 |
| Centers and ends | 16 |
| Centers | 7 |
| Centerpieces | 12 |
| Centerpiece piece | 17 |
| Centerpiece of this puzzle | 26 |
| Centerpiece of some kids' science models | 44 |
| Centerpiece of many a Sunday dinner | 35 |
| Centerpiece of many a park | 26 |
| Centerpiece of Darwinian theory | 31 |
| Centerpiece of a successful line? | 33 |
| Centerpiece | 11 |
| Centering point | 15 |
| Centerfolds, often | 18 |
| Centerfold, maybe | 17 |
| Centerfold, e.g. | 16 |
| Centerfold's pride? | 23 |
| Centerfold sight | 16 |
| Centerfold model | 16 |
| Centerfold measurements, facetiously | 36 |
| Centerfold in Guitar World | 26 |
| Centerfold features | 19 |
| Centerfold art in Cosmopolitan | 30 |
| Centerfold | 10 |
| Centerfielder's position in the scorebook | 46 |
| Centerfield legend Agee | 23 |
| Centered in | 11 |
| Centered (on) | 13 |
| Centered | 8 |
| Center-to-rim lines | 19 |
| Center-to-quarterback transitions | 33 |
| Center-to-quarterback exchange | 30 |
| Center-ring offering | 20 |
| Center, in poesy | 16 |
| Center, for one | 15 |
| Center, classic car, put down, headland | 39 |
| Center's position | 21 |
| Center's place | 18 |
| Center's pass | 17 |
| Center's job | 16 |
| Center's hand-off | 21 |
| Center's duty | 17 |
| Center's chore | 18 |
| Center's action | 19 |
| Center X, in a game | 19 |
| Center X or O | 13 |
| Center X | 8 |
| Center word of a famed palindrome | 33 |
| Center with an MBA | 18 |
| Center Willis | 13 |
| Center where basketball began | 29 |
| Center the football | 19 |
| Center the crosshairs | 21 |
| Center the cross hairs | 22 |
| Center strip cuts? | 18 |
| Center starter? | 15 |
| Center starter | 14 |
| Center start? | 13 |
| Center start | 12 |
| Center stage | 12 |
| Center square on "The Brady Bunch" | 44 |
| Center square of a bingo card | 29 |
| Center square in a game | 23 |
| Center spot | 11 |
| Center Shaquille | 16 |
| Center Shaq | 11 |
| Center prefix | 13 |
| Center preceder | 15 |
| Center piece | 12 |
| Center performance | 18 |
| Center or tackle | 16 |
| Center or gram preceder | 23 |
| Center or gram lead-in | 22 |
| Center or focus | 15 |
| Center or end | 13 |
| Center or cycle opener | 22 |
| Center opening? | 15 |