| Something risky to work on | 26 |
| Something rooted out | 20 |
| Something running on a cell | 27 |
| Something said before grace? | 28 |
| Something said while holding a bag | 34 |
| Something said while shaking? | 29 |
| Something Sajak sells | 21 |
| Something saved for a rainy day | 31 |
| Something scary | 15 |
| Something school kids hope for in December? | 43 |
| Something scored | 16 |
| Something scouted | 17 |
| Something scratched or shaken | 29 |
| Something screwdrivers can help make | 36 |
| Something secondary | 19 |
| Something seen | 14 |
| Something seen after hours? | 27 |
| Something seen by a buck passer | 31 |
| Something seen by bears | 23 |
| Something seen in anger? | 24 |
| Something seen in planners | 26 |
| Something seen on a buck? | 25 |
| Something seen on a pad | 23 |
| Something seen on Forever stamps | 32 |
| Something seen when you're in the clouds? | 45 |
| Something seen with the Virgin Mary | 35 |
| Something seized | 16 |
| Something sensed | 16 |
| Something sent with a click | 27 |
| Something sent with a ltr. | 26 |
| Something served au poivre | 26 |
| Something served in a shell | 27 |
| Something served with espresso | 30 |
| Something set in a place setting | 32 |
| Something set in stone | 22 |
| Something shady | 15 |
| Something shady? | 16 |
| Something shaken on | 19 |
| Something shaken, supposedly | 28 |
| Something she didn't say | 28 |
| Something shed | 14 |
| Something short found in an alley | 33 |
| Something shown off on a half-pipe | 34 |
| Something similar | 17 |
| Something simple | 16 |
| Something simple, supposedly | 28 |
| Something singular | 18 |
| Something sipped with a scone | 29 |
| Something skipped | 17 |
| Something slipped on | 20 |
| Something slipped under the counter? | 36 |
| Something small | 15 |
| Something small to pick | 23 |
| Something smashable | 19 |
| Something smashed by Abraham, in Jewish tradition | 49 |
| Something smoked at an Indian ceremony | 38 |
| Something snapped | 17 |
| Something snobs put on | 22 |
| Something snobs put on? | 23 |
| Something soaked up | 19 |
| Something sold in half sizes | 28 |
| Something sold in spheres | 25 |
| Something some 1970s fad rings purported to indicate | 52 |
| Something some people return from vacation with | 47 |
| Something someone might beg for | 31 |
| Something sometimes coined | 26 |
| Something sometimes irrefusable | 31 |
| Something sometimes smelled | 27 |
| Something sometimes split | 25 |
| Something soothing | 18 |
| Something sought at sinks | 25 |
| Something Spanish | 17 |
| Something sparkling | 19 |
| Something special | 17 |
| Something spectacular or confusing | 34 |
| Something spinach has | 21 |
| Something split for soup | 24 |
| Something split off | 19 |
| Something spoken of at oral exams | 33 |
| Something Spooner might have "flung out" | 50 |
| Something spotted in a toy store | 32 |
| Something spotted in a tree | 27 |
| Something spotted in a tree? | 28 |
| Something spun | 14 |
| Something square to eat? | 24 |
| Something squirreled away | 25 |
| Something staked | 16 |
| Something standing for something else | 37 |
| Something startling | 19 |
| Something stated | 16 |
| Something steeped | 17 |
| Something stereotypical men don't do | 40 |
| Something stolen from Austin Powers | 35 |
| Something stored | 16 |
| Something stored in a garage | 28 |
| Something stored in a shed | 26 |
| Something strained at | 21 |
| Something straining credibility | 31 |
| Something strange | 17 |
| Something stretched in gyms | 27 |