| It's drained by traveling | 29 |
| It's dragged to the altar | 29 |
| It's down, in a Homestar Runner cartoon | 43 |
| It's down the road | 22 |
| It's down the coast from Portland | 37 |
| It's down in the mouth | 26 |
| It's down in the dumps | 26 |
| It's double-hyphenated: Abbr. | 33 |
| It's dotted | 15 |
| It's donned | 15 |
| It's done with a twist | 26 |
| It's done while holding hands | 33 |
| It's done outside a lab | 27 |
| It's done on tiptoe | 23 |
| It's done lying down | 24 |
| It's done in the slammer | 28 |
| It's done in the shape of an S or Z | 39 |
| It's done in the form of an S or a Z | 40 |
| It's done in the can | 24 |
| It's done in some circles | 29 |
| It's done in Maine waters | 29 |
| It's done in France all the time | 36 |
| It's done in cages | 22 |
| It's done for publicity | 27 |
| It's done for fun, for short | 32 |
| It's done for fun | 21 |
| It's done for appearance' sake | 38 |
| It's done by swingers | 25 |
| It's done at psychedelic shows | 34 |
| It's done a lot in church | 29 |
| It's done | 13 |
| It's divided into scenes | 28 |
| It's divided into mysteries | 31 |
| It's divided into comtés | 31 |
| It's divided into chapters | 30 |
| It's divided into 24 books | 30 |
| It's divided in Asia | 24 |
| It's distracting | 20 |
| It's distilled from fermented molasses, often | 49 |
| It's dissolved into a solvent | 33 |
| It's disregarded in alphabetizing | 37 |
| It's disproved with Zener cards | 35 |
| It's disposable online | 26 |
| It's displayed in vain? | 27 |
| It's dispensed from a hose | 30 |
| It's dishwasher-safe | 24 |
| It's dished up in a lab | 27 |
| It's discovered in veins | 28 |
| It's discarded | 18 |
| It's disagreeable to the nose | 33 |
| It's directly perceivable | 29 |
| It's directly below V-B-N-M | 31 |
| It's directly behind the three | 34 |
| It's direct | 15 |
| It's dipped in the water | 28 |
| It's dipped in milk | 23 |
| It's dipped in a dip | 24 |
| It's difficult to see through | 33 |
| It's difficult to find in a haystack | 40 |
| It's dialed before a long-distance number | 45 |
| It's developed in a sonata | 30 |
| It's developed during training season | 41 |
| It's developed after the id | 31 |
| It's detected by the Marsh test, in forensics | 49 |
| It's destined to happen | 27 |
| It's desired while shopping | 31 |
| It's designed to give you a lift | 36 |
| It's designed to come back to you | 37 |
| It's designed to be seen just above the beltline | 52 |
| It's designed not to be noticeable | 38 |
| It's designed for quick entrances | 37 |
| It's deserted in fantasies | 30 |
| It's deserted in dreams | 27 |
| It's derived from the French word "hautbois," meaning "high wood" | 89 |
| It's derived from natural gas | 33 |
| It's depressed for power | 28 |
| It's depressed | 18 |
| It's depreciated with respect to foreign currencies | 55 |
| It's deposited when glacial ice melts | 41 |
| It's deposited in drops | 27 |
| It's depicted on the Sistine Chapel ceiling | 47 |
| It's depicted by a cello melody in "The Carnival of the Animals" | 78 |
| It's denoted by a 1 | 23 |
| It's demonstrated by ring color | 35 |
| It's delivered underhandedly? | 33 |
| It's delivered to millions on Sundays | 41 |
| It's delivered on the gridiron | 34 |
| It's definitely not the short answer | 40 |
| It's definitely not right? | 30 |
| It's definitely not right | 29 |
| It's definitely not good | 28 |
| It's definitely not a yacht | 31 |
| It's definitely a reserved seat | 35 |
| It's definite | 17 |
| It's defeated in "Return of the Jedi" | 51 |
| It's deep, man | 18 |
| It's deep | 13 |
| It's declining in Germany | 29 |
| It's declared after the last hit, for short | 47 |
| It's decisively important to a solution | 43 |