| Certain Southeastern Conference mascot | 38 |
| Certain Southeast Asians | 24 |
| Certain Southeast Asian | 23 |
| Certain South Asian | 19 |
| Certain South Americans | 23 |
| Certain South American Indian | 29 |
| Certain South American capital | 30 |
| Certain South American | 22 |
| Certain South Africans | 22 |
| Certain South African | 21 |
| Certain source of nighttime arousal | 35 |
| Certain source of illumination | 30 |
| Certain source of clothing | 26 |
| Certain soup carrier | 20 |
| Certain sounds | 14 |
| Certain soundboard knobs | 24 |
| Certain sound from the lips | 27 |
| Certain sound | 13 |
| Certain sorters | 15 |
| Certain sort of souse | 21 |
| Certain sorority women | 22 |
| Certain sorority woman | 22 |
| Certain sorority members | 24 |
| Certain sorority member | 23 |
| Certain sorority girl | 21 |
| Certain sorority chapter | 24 |
| Certain sore spots | 18 |
| Certain sorcerer's aide: Abbr. | 34 |
| Certain Sopwith Scout | 21 |
| Certain soprano | 15 |
| Certain Sooner | 14 |
| Certain songs | 13 |
| Certain songbird | 16 |
| Certain song? | 13 |
| Certain somethings, so to speak | 31 |
| Certain something about someone | 31 |
| Certain something | 17 |
| Certain solvents | 16 |
| Certain solutions | 17 |
| Certain solution holder | 23 |
| Certain soluble salts | 21 |
| Certain soloist? | 16 |
| Certain solo | 12 |
| Certain soldiers: Abbr. | 23 |
| Certain soldiers | 16 |
| Certain soldier | 15 |
| Certain software downloads | 26 |
| Certain softball pitch | 22 |
| Certain soft drink buys | 23 |
| Certain soft drink | 18 |
| Certain soft cheese | 19 |
| Certain sofa | 12 |
| Certain sodas | 13 |
| Certain soda | 12 |
| Certain sock | 12 |
| Certain society | 15 |
| Certain social system | 21 |
| Certain social networking update | 32 |
| Certain social gathering | 24 |
| Certain soap, initially | 23 |
| Certain snowman | 15 |
| Certain snow jobs | 17 |
| Certain snow field | 18 |
| Certain snow construction | 25 |
| Certain sneakers | 16 |
| Certain snares | 14 |
| Certain snake's warning words | 33 |
| Certain snake or car | 20 |
| Certain snake | 13 |
| Certain snack cakes | 19 |
| Certain smokes | 14 |
| Certain smoke signal | 20 |
| Certain smith | 13 |
| Certain smasher's target | 28 |
| Certain smasher input | 21 |
| Certain smartphone | 18 |
| Certain small vegetable | 23 |
| Certain small planes | 20 |
| Certain small musical group | 27 |
| Certain small monkey | 20 |
| Certain small fry | 17 |
| Certain sluts | 13 |
| Certain slow-moving creature | 28 |
| Certain slow pitch | 18 |
| Certain slitherer | 17 |
| Certain slippers | 16 |
| Certain slip-on, briefly | 24 |
| Certain slip-on | 15 |
| Certain sliding bolts | 21 |
| Certain sleep stages, in brief | 30 |
| Certain sleep problem | 21 |
| Certain sled riders | 19 |
| Certain sled driver | 19 |
| Certain Slavs | 13 |
| Certain Slav | 12 |
| Certain slacks | 14 |
| Certain skullcap | 16 |
| Certain skirts | 14 |
| Certain skirt material | 22 |
| Certain skirt | 13 |