| Mrs. Shriver | 12 |
| Mrs. Shrek | 10 |
| Mrs. Shakespeare | 16 |
| Mrs. Schwarzenegger | 19 |
| Mrs. Schumann | 13 |
| Mrs. Schott, owner of the Cincinnati Reds | 41 |
| Mrs. Santa Claus, long ago | 26 |
| Mrs. Sadat | 10 |
| Mrs. Roy Rogers et al. | 22 |
| Mrs. Roy Rogers | 15 |
| Mrs. Roosevelt's first name | 31 |
| Mrs. Roosevelt | 14 |
| Mrs. Romney | 11 |
| Mrs. Rodriguez, e.g. | 20 |
| Mrs. Rodham, to Clinton | 23 |
| Mrs. Rod Stewart | 16 |
| Mrs. Rocky Balboa | 17 |
| Mrs. Rockefeller | 16 |
| Mrs. Rochester, eventually | 26 |
| Mrs. Rochester's kin | 24 |
| Mrs. Robinson: ___ Bancroft | 27 |
| Mrs. Robinson's movie | 25 |
| Mrs. Robinson's girl | 24 |
| Mrs. Robinson's daughter, in "The Graduate" | 57 |
| Mrs. Robinson's daughter | 28 |
| Mrs. Robinson portrayer Bancroft | 32 |
| Mrs. Robinson | 13 |
| Mrs. Robert ___ (Mary Custis) | 29 |
| Mrs. Robert F. Kennedy | 22 |
| Mrs. Rob Petrie | 15 |
| Mrs. Reed's creator | 23 |
| Mrs. Reagan, once | 17 |
| Mrs. Ram | 8 |
| Mrs. Ralph Kramden | 18 |
| Mrs. Rajiv Gandhi | 17 |
| Mrs. Rajah | 10 |
| Mrs. Rabin of Israel | 20 |
| Mrs. Rabin | 10 |
| Mrs. Prynne, of "Private Lives" | 41 |
| Mrs. Prynne of "Private Lives" | 40 |
| Mrs. Priest and others | 22 |
| Mrs. Potts's son, in "Beauty and the Beast" | 57 |
| Mrs. Portnoy, in "Portnoy's Complaint" | 52 |
| Mrs. Ponti's maiden name | 28 |
| Mrs. Ponti | 10 |
| Mrs. Pollifax creator Dorothy | 29 |
| Mrs. Polk | 9 |
| Mrs. Philip Mountbatten | 23 |
| Mrs. Phil Harris | 16 |
| Mrs. Peron et al. | 17 |
| Mrs. Peron | 10 |
| Mrs. Perón | 17 |
| Mrs. Peel's partner | 23 |
| Mrs. Peel's job | 19 |
| Mrs. Peel portrayer Diana | 25 |
| Mrs. Peel portrayer | 19 |
| Mrs. Peel player | 16 |
| Mrs. Peel on "The Avengers" | 37 |
| Mrs. Peel on ''The Avengers'' | 45 |
| Mrs. Peel of "The Avengers" | 37 |
| Mrs. Peel from "The Avengers" | 39 |
| Mrs. Peacock's game | 23 |
| Mrs. Paul Simon | 15 |
| Mrs. Paul McCartney | 19 |
| Mrs. Parks from Montgomery | 26 |
| Mrs. Parks | 10 |
| Mrs. Ozzy Osbourne | 18 |
| Mrs. Oskar Schindler | 20 |
| Mrs. Oop | 8 |
| Mrs. Onassis | 12 |
| Mrs. Oliver Wendell Douglas | 27 |
| Mrs. of TV and film | 19 |
| Mrs. of Mexico | 14 |
| Mrs. of legend | 14 |
| Mrs. Odysseus | 13 |
| Mrs. Odin | 9 |
| Mrs. O'___ cow | 18 |
| Mrs. O'Leary did it | 23 |
| Mrs. O'Connor and colleagues | 32 |
| Mrs. Norton of "The Honeymooners" | 43 |
| Mrs. Norris in the "Harry Potter" books, e.g. | 55 |
| Mrs. Nixon, ___ Ryan | 20 |
| Mrs. Nixon at a White House reception | 37 |
| Mrs. Nixon | 10 |
| Mrs. Nicolas Cage, for 108 days | 31 |
| Mrs. Nick Charles et al. | 24 |
| Mrs. Nick Charles | 17 |
| Mrs. Murphy's creations | 27 |
| Mrs. Munster et al. | 19 |
| Mrs. Munster | 12 |
| Mrs. Munchhausen e.g. | 22 |
| Mrs. Mulder on "The X-Files" | 38 |
| Mrs. Muir's friend | 22 |
| Mrs. Muir's beau | 20 |
| Mrs. Morgenstern player on "Rhoda" | 44 |
| Mrs. Morgenstern on "Rhoda" | 37 |
| Mrs. Morgenstern of "Rhoda" | 37 |
| Mrs. Mitt Romney | 16 |
| Mrs. Miniver's husband in "Mrs. Miniver" | 54 |
| Mrs. Miller's partner, in a 1971 film | 41 |