| Trouble bubble contents | 23 |
| Trouble constantly | 18 |
| Trouble en masse | 16 |
| Trouble for a bowler | 20 |
| Trouble for a tomb raider | 25 |
| Trouble for a tooth | 19 |
| Trouble for Suze on a cruise? | 29 |
| Trouble for the hopelessly trapped | 34 |
| Trouble greatly | 15 |
| Trouble in a Shakespeare title | 30 |
| Trouble in France | 17 |
| Trouble in Paradise | 19 |
| Trouble in the night | 20 |
| Trouble in the wind section | 27 |
| Trouble indicator | 17 |
| Trouble makers | 14 |
| Trouble no end | 14 |
| Trouble on a weather map | 24 |
| Trouble on the road, briefly | 28 |
| Trouble on the road: Abbr. | 26 |
| Trouble on the set | 18 |
| Trouble partner | 15 |
| Trouble partner, in Shakespeare | 31 |
| Trouble persistently | 20 |
| Trouble quantity? | 17 |
| Trouble removing a chemical peel, say? | 38 |
| Trouble sign | 12 |
| Trouble spot | 12 |
| Trouble spot for Indiana Jones | 30 |
| Trouble spots for teens | 23 |
| Trouble spots of 1960's | 27 |
| Trouble spots? | 14 |
| Trouble terribly | 16 |
| Trouble with a lid? | 19 |
| Trouble with the stomach lining | 31 |
| Trouble with Zs? | 16 |
| Trouble's mate | 18 |
| Trouble's partner | 21 |
| Trouble's partner, in Shakespeare | 37 |
| Trouble, debt-wise | 18 |
| Trouble, for a prankster | 24 |
| Trouble, in a Shakespeare title | 31 |
| Trouble, in a way | 17 |
| Trouble, in Ayr | 15 |
| Trouble, informally, with "the" | 41 |
| Trouble, so to speak | 20 |
| Trouble-bound | 13 |
| Trouble-free | 12 |
| Trouble-free lands | 18 |
| Trouble-free place | 18 |
| Trouble-maker | 13 |
| Trouble-making Norse god | 24 |
| Trouble-ridden | 14 |
| Trouble-shoot software | 22 |
| Troubled | 8 |
| Troubled (by) | 13 |
| Troubled a lot | 14 |
| Troubled actor Nick | 19 |
| Troubled capital | 16 |
| Troubled conditions | 19 |
| Troubled continent | 18 |
| Troubled continually | 20 |
| Troubled cry | 12 |
| Troubled greatly | 16 |
| Troubled Gyllenhaal character of 2001 | 37 |
| Troubled industry, these days | 29 |
| Troubled insurance giant | 24 |
| Troubled king | 13 |
| Troubled Mideast region | 23 |
| Troubled person's problems | 30 |
| Troubled planet | 15 |
| Troubled region | 15 |
| Troubled region of Europe, with "The" | 47 |
| Troubled Russian region | 23 |
| Troubled sound | 14 |
| Troubled state | 14 |
| Troubled Strip | 14 |
| Troubled terribly | 17 |
| Troubled times for many | 23 |
| Troubled trees | 14 |
| Troubled water's smoother | 29 |
| Troubled waters' soother | 28 |
| Troubled world area | 19 |
| Troubled years, usually | 23 |
| Troubled youth literally hiding in each answer to a starred clue | 64 |
| Troublemaker | 12 |
| Troublemaker in Troy | 20 |
| Troublemaker invented by the British Royal Air Force | 52 |
| Troublemaker of folklore | 24 |
| Troublemaker of myth | 20 |
| Troublemaker's credo? | 25 |
| Troublemaker, perhaps | 21 |
| Troublemaker, politely | 22 |
| Troublemaker, to Marxian purists | 32 |
| Troublemakers | 13 |
| Troublemakers at meetings | 25 |
| Troublemakers, at times | 23 |
| Troublemakers, never | 20 |
| Troublemaking chipmunk | 22 |
| Troublemaking Norse god | 23 |