| Discoverer of six comets | 24 |
| Discoverer of The Miracles | 26 |
| Discoverer of the Mississippi | 29 |
| Discoverer's cries | 22 |
| Discoverer's interjection | 29 |
| Discoverer's outcry | 23 |
| Discoverer's shout | 22 |
| Discoverer's shouts | 23 |
| Discoverers' cries | 22 |
| Discoverers' shouts | 23 |
| Discoveries, colloquially | 25 |
| Discovers unexpectedly | 22 |
| Discovery accompaniers | 22 |
| Discovery Channel subj. | 23 |
| Discovery of Eric the Red | 25 |
| Discovery of March 13, 1781 | 27 |
| Discovery of the mother lode? | 29 |
| Discovery One computer | 22 |
| Discovery sister network | 24 |
| Discovery sister station | 24 |
| Discovery summer highlight | 26 |
| Discovery/design dept. | 22 |
| Discredited, as a theory | 24 |
| Discredited, as an idol | 23 |
| Discreet attention-getter | 25 |
| Discreet email letters | 22 |
| Discreet product packaging | 26 |
| Discrete attention-getter | 25 |
| Discretionary increase? | 23 |
| Discriminates, in a way | 23 |
| Discriminating sort, in a way | 29 |
| Discrimination based on years | 29 |
| Discrimination fighter: Abbr. | 29 |
| Discrimination of sorts | 23 |
| Discriminators of a sort | 24 |
| Discriminatory leader? | 22 |
| Discriminatory practice | 23 |
| Discriminatory, as in hiring | 28 |
| Discriminatory, in a way | 24 |
| Discs for the disco set | 23 |
| Discus thrower Oerter et al. | 28 |
| Discus thrower's activity | 29 |
| Discus ___ (aquarium fish) | 26 |
| Discuss business, in a way | 26 |
| Discuss from various angles | 27 |
| Discuss the pros and cons of | 28 |
| Discuss, with “over” | 28 |
| Discussed one's business | 28 |
| Discusses the issue, at last | 28 |
| Discussion among netizens | 25 |
| Discussion contribution | 23 |
| Discussion group choice | 23 |
| Discussion group members | 24 |
| Discussion of both sides | 24 |
| Discussion opportunity | 22 |
| Discussion with rocker Billy? | 29 |
| Discussion-ending words | 23 |
| Discussion-group member | 23 |
| Disdain ... rank ... high-hat | 29 |
| Disdain for the unattainable | 28 |
| Disdainful exclamation | 22 |
| Disdainful expressions | 22 |
| Disdainful interjection | 23 |
| Disdainful upperclassman? | 25 |
| Disdainful, pouting grimace | 27 |
| Disease also called pertussis | 29 |
| Disease caught from birds | 25 |
| Disease caused by strep | 23 |
| Disease diagnosed by dentists | 29 |
| Disease of cereal grasses | 25 |
| Disease of domestic animals | 27 |
| Disease of overripe fruit | 25 |
| Disease of sweet potatoes | 25 |
| Disease spread by mosquitoes | 28 |
| Disease with muscular spasms | 28 |
| Disease-carrying flies | 22 |
| Disease-carrying insect | 23 |
| Disease-carrying mosquito | 25 |
| Disease-causing bacteria | 24 |
| Disease-causing microorganism | 29 |
| Disease-fighting protein | 24 |
| Disease-free sea predators? | 27 |
| Diseased parts of wood | 22 |
| Diseased Subhumans song? | 24 |
| Diseases of grapevines | 22 |
| Disembark at O'Hare | 23 |
| Disembarked from a jet | 22 |
| Disembodied sci-fi antagonist | 29 |
| Disembodied souls, in Judaism | 29 |
| Disenchanted fan, at times | 26 |
| Disengaged, as an engine | 24 |
| Disengages from a habit | 23 |
| Disengages, as a clutch | 23 |
| Disengages, as from a habit | 27 |
| Disentangle after a tackle | 26 |
| Disentangle, as fishing line | 28 |
| Disentangle, in football | 24 |
| Disentangled, as fibers | 23 |
| Disfigurement on a car | 22 |
| Disgraced cyclist Armstrong | 27 |