| Responded unintelligibly | 24 |
| Responded villainously | 22 |
| Respondent to a challenge | 25 |
| Responder in a van: Abbr. | 25 |
| Responder to O on the dial | 26 |
| Responder trained in CPR | 24 |
| Responding to a stimulus | 24 |
| Responds to a busy signal | 25 |
| Responds to a cue, in a way | 27 |
| Responds to a cue, maybe | 24 |
| Responds to a Facebook event | 28 |
| Responds to a magician, maybe | 29 |
| Responds to a morning alarm | 27 |
| Responds to a stimulus | 22 |
| Responds to Alex Trebek | 23 |
| Responds to another change | 26 |
| Responds to heat, in a way | 26 |
| Responds to kitchen aromas | 26 |
| Responds to the MAILER-DAEMON | 29 |
| Responds well to a joke | 23 |
| Response after knocking | 23 |
| Response at an unveiling | 24 |
| Response at the bridge table | 28 |
| Response bias may affect one | 28 |
| Response facilitator: Abbr. | 27 |
| Response from a bonny lass? | 27 |
| Response from an unbeliever | 27 |
| Response from another room | 26 |
| Response from Gary Cooper | 25 |
| Response from the awed | 22 |
| Response from the faithful | 26 |
| Response from the flock | 23 |
| Response from the next room | 27 |
| Response in a guessing game | 27 |
| Response of feigned innocence | 29 |
| Response of mock subservience | 29 |
| Response to 'Am so!' | 28 |
| Response to "Achoo" | 29 |
| Response to "Here?" | 29 |
| Response to "Look!" | 29 |
| Response to "POW!" | 28 |
| Response to a back scratch | 26 |
| Response to a backstabber | 25 |
| Response to a bad call | 22 |
| Response to a brother? | 22 |
| Response to a cape flourish | 27 |
| Response to a capitán | 24 |
| Response to a carping person | 28 |
| Response to a catty comment | 27 |
| Response to a catty remark | 26 |
| Response to a cave shout | 24 |
| Response to a come-on, maybe | 28 |
| Response to a compliment | 24 |
| Response to a court oath | 24 |
| Response to a crumpled fax | 26 |
| Response to a dad joke, say | 27 |
| Response to a delegation? | 25 |
| Response to a ding-dong? | 24 |
| Response to a disbeliever | 25 |
| Response to a doorbell | 22 |
| Response to a double entendre | 29 |
| Response to a double-crosser | 28 |
| Response to a doubting Thomas | 29 |
| Response to a drought ending | 28 |
| Response to a fencing lunge | 27 |
| Response to a fireworks show | 28 |
| Response to a fleecing? | 23 |
| Response to a funny text | 24 |
| Response to a gag, perhaps | 26 |
| Response to a good barb | 23 |
| Response to a good dig | 22 |
| Response to a great retort | 26 |
| Response to a gut punch | 23 |
| Response to a joke in an I.M. | 29 |
| Response to a joke on-line | 26 |
| Response to a kissing bandit | 28 |
| Response to a knock, maybe | 26 |
| Response to a knock, perhaps | 28 |
| Response to a laryngologist | 27 |
| Response to a lousy deal | 24 |
| Response to a minister | 22 |
| Response to a naysayer | 22 |
| Response to a one-liner | 23 |
| Response to a pass, perhaps | 27 |
| Response to a pinch, perhaps | 28 |
| Response to a pinprick | 22 |
| Response to a polar vortex | 26 |
| Response to a preacher | 22 |
| Response to a proposal | 22 |
| Response to a pun, perhaps | 26 |
| Response to a punch, perhaps | 28 |
| Response to a revelation | 24 |
| Response to a rude advance | 26 |
| Response to a rude remark | 25 |
| Response to a sales clerk | 25 |
| Response to a scarecrow | 23 |
| Response to a sharp rejoinder | 29 |
| Response to a shot, maybe | 25 |
| Response to a site gag? | 23 |
| Response to a stimulus | 22 |