| South American squawker | 23 |
| South American spread owner | 27 |
| South American spitters | 23 |
| South American soccer hero | 26 |
| South American snack | 20 |
| South American singer/French writer | 35 |
| South American singer Sumac | 27 |
| South American simian | 21 |
| South American silver | 21 |
| South American shrubs with potent leaves | 40 |
| South American setting of Hitchcock's "Notorious" | 63 |
| South American seaport | 22 |
| South American ruminant | 23 |
| South American rodents | 22 |
| South American rodent | 21 |
| South American river in an Enya song title | 42 |
| South American river | 20 |
| South American resort | 21 |
| South American republic | 23 |
| South American reptile | 22 |
| South American ratites | 22 |
| South American ratite | 21 |
| South American range | 20 |
| South American race | 19 |
| South American raccoon | 22 |
| South American prairies | 23 |
| South American prairie | 22 |
| South American plant | 20 |
| South American plains | 21 |
| South American plain | 20 |
| South American pipsqueaks | 25 |
| South American peaks | 20 |
| South American parrot | 21 |
| South American pack animal | 26 |
| South American ostriches | 24 |
| South American opening trendy lunch dish (5) | 44 |
| South American natives | 22 |
| South American native | 21 |
| South American nation | 21 |
| South American Mrs. | 19 |
| South American mountains | 24 |
| South American mountain range | 29 |
| South American mountain chain | 29 |
| South American monkeys | 22 |
| South American monkey with a long tail | 38 |
| South American monkey | 21 |
| South American misfit? | 22 |
| South American menace | 21 |
| South American marmoset | 23 |
| South American mammals | 22 |
| South American mammal | 21 |
| South American lowlands | 23 |
| South American llama | 20 |
| South American lizard | 21 |
| South American liberator | 24 |
| South American lasso | 20 |
| South American land | 19 |
| South American lake | 19 |
| South American kin | 18 |
| South American killer | 21 |
| South American invention | 24 |
| South American Indian | 21 |
| South American herd members | 27 |
| South American herd | 19 |
| South American hawk | 19 |
| South American grilling style | 29 |
| South American grilled meat dish | 32 |
| South American grazer | 21 |
| South American grassland | 24 |
| South American freshwater shockers | 34 |
| South American forest dweller | 29 |
| South American football player? | 31 |
| South American flower | 21 |
| South American fleece source | 28 |
| South American fiber plant | 26 |
| South American fellow? | 22 |
| South American empire of yore | 29 |
| South American empire | 21 |
| South American dance | 20 |
| South American cruise stop, for short | 37 |
| South American cruise stop | 26 |
| South American creature | 23 |
| South American cowboy | 21 |
| South American country with a red-and-white flag | 48 |
| South American country at 0 degrees lat. | 40 |
| South American country | 22 |
| South American constrictor | 26 |
| South American coastal region that includes Suriname | 52 |
| South American coastal region | 29 |
| South American coastal country | 30 |
| South American civilization | 27 |
| South American city to be blamed, per a 1984 movie title | 56 |
| South American city of 2 million | 32 |
| South American city | 19 |
| South American chain | 20 |
| South American celebration | 26 |
| South American cattle-catcher | 29 |
| South American cattle catcher | 29 |
| South American carrier founded in 1927 | 38 |
| South American carrier | 22 |