| Clues | 5 |
| Cluelessness gesture | 20 |
| Clueless-inspired Sara Evans song? | 34 |
| Clueless, after "in" | 30 |
| Clueless sort | 13 |
| Clueless response | 17 |
| Clueless reply | 14 |
| Clueless one's response | 27 |
| Clueless one's comment | 26 |
| Clueless expression | 19 |
| Clueless emcee? | 15 |
| Clueless amphibian? | 19 |
| Clueless "Skyrim" player, e.g. | 40 |
| Clueless exclamation | 23 |
| Clueless | 8 |
| Clued-in regarding | 18 |
| Clued in, once | 14 |
| Clued in regarding | 18 |
| Clued in about | 14 |
| Clued in | 8 |
| Clued | 5 |
| Clue-sniffing dog | 17 |
| Clue, for one | 13 |
| Clue, e.g. | 10 |
| Clue's Plum, briefly | 24 |
| Clue's Mr. Boddy, e.g. | 26 |
| Clue weapon | 11 |
| Clue to this puzzle's theme | 31 |
| Clue to the second word of the mystery phrase | 45 |
| Clue to how "rate mortgage" is adjustable herein | 58 |
| Clue to homo sapiens? | 21 |
| Clue that's discovered by dusting | 37 |
| Clue that started this all | 26 |
| Clue that helped convict a movie snack thief? | 45 |
| Clue that coffee's on | 25 |
| Clue suspect | 12 |
| Clue space | 10 |
| Clue sniffer of fiction | 23 |
| Clue seeker: Abbr. | 18 |
| Clue room | 9 |
| Clue requisite | 14 |
| Clue professor | 14 |
| Clue outlets | 12 |
| Clue or Life | 12 |
| Clue or cue | 11 |
| Clue or backgammon, e.g. | 24 |
| Clue option | 11 |
| Clue on a weapon | 16 |
| Clue of a sort | 14 |
| Clue markers (abbr.) | 20 |
| Clue locale perhaps | 20 |
| Clue left by a podiatrist while filching pepper? | 48 |
| Clue left by a newlywed while raiding freezers? | 47 |
| Clue left by a builder while swiping golf balls? | 48 |
| Clue left by a boxer while robbing banks? | 41 |
| Clue is one | 11 |
| Clue interpreters | 17 |
| Clue in a hunt | 14 |
| Clue in a case | 14 |
| Clue in 'The Da Vinci Code' | 35 |
| Clue in | 7 |
| Clue hunters, slangily | 22 |
| Clue hunter, informally | 23 |
| Clue heading | 12 |
| Clue gatherer: Abbr. | 20 |
| Clue game board space | 21 |
| Clue from Trebek | 16 |
| Clue for this puzzle's four longest answers | 47 |
| Clue for the southwest corner | 29 |
| Clue for the southeast corner | 29 |
| Clue for the northwest corner | 29 |
| Clue for the northeast corner | 29 |
| Clue for the four longest answers in this puzzle | 48 |
| Clue for the clueless | 21 |
| Clue for Kojak | 14 |
| Clue for Holmes | 15 |
| Clue for half of these clues | 28 |
| Clue for four puzzle answers | 28 |
| Clue for Batman, maybe | 22 |
| Clue for a car mechanic | 23 |
| Clue for a bloodhound | 21 |
| Clue follower | 13 |
| Clue finders | 12 |
| Clue designed to mislead | 24 |
| Clue crew | 9 |
| Clue collector, slangily | 24 |
| Clue choice | 11 |
| Clue board section | 18 |
| Clue analyzer, in slang | 23 |
| Clue accusation piece | 21 |
| Clue academic | 13 |
| Clue about new album | 20 |
| CLUE #4 | 7 |
| CLUE #3 | 7 |
| CLUE #1 | 7 |
| Clue | 4 |
| Clucks of disdain | 17 |
| Clucks of disapproval | 21 |
| Clucks of disappointment | 24 |
| Clucks in a reprimand | 21 |