| A screen Chan | 13 |
| A screw loose | 13 |
| A script, in printing | 21 |
| A Scrooge portrayer | 19 |
| A scuttle might scoop from it | 29 |
| A scythe may cut one | 20 |
| A sea | 5 |
| A sea mon ami | 14 |
| A sea was named for him | 23 |
| A seamstress should be __ | 25 |
| A search may be done with it | 28 |
| A season abroad | 15 |
| A season in India, with "the" | 39 |
| A season in Sedan | 17 |
| A season, in Arles | 18 |
| A season: Abbr. | 15 |
| A seasoning | 11 |
| A seasoning, in Savoie | 22 |
| A señor has one | 18 |
| A Sec. of Treasury under Truman | 31 |
| A second helping | 16 |
| A second self | 13 |
| A second shift, possibly | 24 |
| A second time | 13 |
| A secret may be told in one | 27 |
| A secretary might take it | 25 |
| A Secretary of State for F.D.R. | 31 |
| A section of New York City that sounds like a person | 52 |
| A section of Yankee Stadium's golf course? | 46 |
| A security | 10 |
| A security guard might ask you to do this | 41 |
| A security guard might be on this | 33 |
| A secy might take one from a CEO | 32 |
| A sedge of ______ | 18 |
| A Sedge of ______ | 17 |
| A Sedgwick | 10 |
| A seed might get one | 20 |
| A seeming eternity | 18 |
| A seemingly endless series | 26 |
| A seer may read them | 20 |
| A semi lacks a front one | 24 |
| A semi might make one | 21 |
| A semihard yellow cheese | 24 |
| A seminomadic Muslim | 20 |
| A semirural area | 16 |
| A semisolid | 11 |
| A Semite | 8 |
| A Semitic language | 18 |
| A Senator from Ga. | 18 |
| A sense | 7 |
| A sensor | 8 |
| A sentence | 10 |
| A Sentimental Journey author | 31 |
| A Seoul G.I. | 12 |
| A September sign | 16 |
| A sergeant may order one | 24 |
| A sergeant might ask a soldier to pick it up | 44 |
| A sergeant might ask soldiers to pick it up | 43 |
| A series of "insurmountable obstacles on the road to imminent disaster," per Tom Stoppard | 99 |
| A series of chirps | 18 |
| A series of curls | 17 |
| A series of disasters | 21 |
| A series of skits | 17 |
| A Serious Man filmmakers | 24 |
| A serious one may be red | 24 |
| A sermon of Buddha | 18 |
| A serous fluid | 14 |
| A servant in "The Taming . . . " | 42 |
| A service break might break one | 31 |
| A service winner | 16 |
| A serving of grog or rum | 24 |
| A Sesame Streeter | 17 |
| A set for ''The White Shadow'' | 46 |
| A set of bks. | 13 |
| A Seton | 7 |
| A setting for "The Student Prince" | 44 |
| A Seven Sisters school | 22 |
| A seven-footer, quite often | 27 |
| A seventh-century date | 22 |
| A seventh-century Irish bishop who became a saint | 49 |
| A Severn feeder | 15 |
| A Sevillian | 11 |
| A sew-and-sew? | 14 |
| A sewer has one | 15 |
| A Sex Pistol | 12 |
| A shade of beige | 16 |
| A shade of blue | 15 |
| A shade of green | 16 |
| A shade of red | 14 |
| A shady group | 13 |
| A shaft | 7 |
| A shake in the grass? | 21 |
| A Shakespeare contemporary | 26 |
| A shaman uses them | 18 |
| A shark may carry one | 21 |
| A shark might give you one | 26 |
| A sharp | 7 |
| A sharp key? | 12 |
| A sharp, by another name | 24 |
| A sharpshooter needs a good one | 31 |