| Four on some old faces | 22 |
| Four on the ground, maybe | 25 |
| Four or larceny | 15 |
| Four or point | 13 |
| Four or six follower | 20 |
| Four p.m. affair | 16 |
| Four p.m. to midnight, to factory workers | 41 |
| Four pairs | 10 |
| Four pairs united | 17 |
| FOUR PAPER CHASERS | 18 |
| Four parts | 10 |
| Four parts gin one part vermouth | 33 |
| Four parts? | 11 |
| Four pecks | 10 |
| Four pills instead of the recommended two | 41 |
| Four pks. | 9 |
| Four posters | 12 |
| Four preceder | 13 |
| Four properties on a Monopoly bd. | 33 |
| Four qts. | 9 |
| Four quarters | 13 |
| Four quarters' equivalent | 29 |
| Four quarters, in France | 24 |
| Four quarters, in Quito | 23 |
| Four quarters, to a Jet | 23 |
| Four quarts | 11 |
| Four quarts: Abbr. | 18 |
| Four Questions event | 20 |
| Four RED things | 15 |
| Four Roman ones? | 16 |
| Four roods | 10 |
| Four rows at the Palace | 23 |
| Four sands | 10 |
| Four score | 10 |
| Four score and ten | 18 |
| Four scoreless quarters | 23 |
| Four seasons | 12 |
| Four seasons from now | 21 |
| Four Seasons hit, "Save ___ Me" | 41 |
| Four Seasons Hotel architect | 28 |
| Four Seasons Hotels headquarters | 32 |
| Four seasons in Baja | 20 |
| Four seasons in Madrid | 22 |
| Four seasons in Seville | 23 |
| Four seasons in Sonora | 22 |
| Four seasons in Spain | 21 |
| Four Seasons leader | 19 |
| Four Seasons number, e.g. | 25 |
| Four Seasons offering | 21 |
| Four Seasons song | 17 |
| Four seasons, e.g. | 18 |
| Four Seasons, for one | 21 |
| Four SeasonsÂ’ hotel competitor | 34 |
| Four shots | 10 |
| Four sights as "Hamlet" ends | 38 |
| Four six-packs | 14 |
| Four song releases, typically | 29 |
| Four spot? | 10 |
| Four SQUAREs | 12 |
| Four stars, perhaps | 19 |
| Four stars, say | 15 |
| Four stops on "A" trip around the world | 49 |
| Four straight wins to start the World Series, e.g. | 50 |
| Four strikeouts by a batter in a single game | 44 |
| Four sun followers | 18 |
| Four teeth | 10 |
| Four thirds, for example | 24 |
| Four time AL batting champ | 26 |
| Four times | 10 |
| Four times 25.25 | 16 |
| Four times a day, in an Rx | 26 |
| Four times a day, in prescriptions | 34 |
| Four times a day, on an Rx | 26 |
| Four times a day: Abbr. | 23 |
| Four times a year: Abbr. | 24 |
| Four times daily, in an Rx | 26 |
| Four times what's left? | 27 |
| Four times XIII | 15 |
| Four times? | 11 |
| Four to Flavius | 15 |
| Four Tops "It's the ___ Old Song" | 47 |
| Four Tops frontman Stubbs | 25 |
| Four Tops hit of 1965 | 21 |
| Four Tops singer's soaking spots? | 37 |
| Four Tops smash hit | 19 |
| Four Tops tune, e.g. | 20 |
| Four Tops-inspired Mudvayne song? | 33 |
| Four trimesters | 15 |
| Four types of shots | 19 |
| Four ways to get around | 23 |
| Four Weddings ____ Funeral | 30 |
| Four were Triple | 16 |
| Four Wheeler's 2009 SUVs of the Year | 40 |
| Four WHITE things | 17 |
| Four winter wks. | 16 |
| Four words with paper | 21 |
| Four words with strings attached | 32 |
| Four years as governor, say | 27 |
| Four years at 1600, e.g. | 24 |
| Four years for a U.S. president | 31 |