| Second-highest part, usually | 28 |
| Second-highest pinochle card | 28 |
| Second-highest pinochle cards | 29 |
| Second-highest world capital | 28 |
| Second-in-command: abbr. | 24 |
| Second-largest city in Ark. | 27 |
| Second-largest city in Italy | 28 |
| Second-largest city of Italia | 29 |
| Second-largest continent | 24 |
| Second-largest country | 22 |
| Second-largest existing bird | 28 |
| Second-largest Great Lake | 25 |
| Second-largest Greek island | 27 |
| Second-largest human bone | 25 |
| Second-largest Indian city | 26 |
| Second-largest lake in Europe | 29 |
| Second-largest land animal | 26 |
| Second-largest living bird | 26 |
| Second-largest living birds | 27 |
| Second-largest Med. island | 26 |
| Second-largest moon of Saturn | 29 |
| Second-largest of seven | 23 |
| Second-largest religion | 23 |
| Second-largest Saturnian moon | 29 |
| Second-largest Siberian city | 28 |
| Second-largest Syrian city | 26 |
| Second-largest US island | 24 |
| Second-lightest noble gas | 25 |
| Second-longest Bible book | 25 |
| Second-longest human bone | 25 |
| Second-longest Polish river | 27 |
| Second-longest river of China | 29 |
| Second-lowest poker card | 24 |
| Second-most-populous country | 28 |
| Second-oldest N.L. stadium | 26 |
| Second-oldest US monthly | 24 |
| Second-oldest US record label | 29 |
| Second-place contender | 22 |
| Second-place contestant | 23 |
| Second-place finishers | 22 |
| Second-place Olympic athletes | 29 |
| Second-quality, as mdse. | 24 |
| Second-rank chess piece | 23 |
| Second-rate prizefighter | 24 |
| Second-sequel indicator | 23 |
| Second-simplest hydrocarbon | 27 |
| Second-smallest continent | 25 |
| Second-smallest S.A. country | 28 |
| Second-smallest state: Abbr. | 28 |
| Second-smallest Teletubby | 25 |
| Second-smallest U.S. state | 26 |
| Second-story man's crime | 28 |
| Second-string coll. teams | 25 |
| Second-string players? | 22 |
| Second-string QB, often | 23 |
| Second-tier, among celebs | 25 |
| Second-to-last digit, often | 27 |
| Second-wave feminist Jong | 25 |
| Second-year coll. students | 26 |
| Second-year student, briefly | 28 |
| Second-year student, shortly | 28 |
| Second-year students, briefly | 29 |
| Second-year, for short | 22 |
| Second-youngest March sister | 28 |
| Secondary arrangements | 22 |
| Secondary bank, for example | 27 |
| Secondary course of study | 25 |
| Secondary education building | 28 |
| Secondary field of study | 24 |
| Secondary item in a newspaper | 29 |
| Secondary legal actions | 23 |
| Secondary letter addenda | 24 |
| Secondary rail track: Abbr. | 27 |
| Secondary railroad line | 23 |
| Secondary school, in France | 27 |
| Secondary sports event | 22 |
| Secondary thoroughfare | 22 |
| Secondary-school club? | 22 |
| Seconder's opinion | 22 |
| Secondhand gal of song | 22 |
| Secondhand store section | 24 |
| Secondhand store transaction | 28 |
| Secondhand store transactions | 29 |
| Secondhand tire, perhaps | 24 |
| Secondhand transaction | 22 |
| Secondhand transactions | 23 |
| Secondmost populous place | 25 |
| Seconds and then thirds | 23 |
| Seconds at the dinner table | 27 |
| Seconds participate in them | 27 |
| Secrecy, with "the" | 29 |
| Secret agent's need | 23 |
| Secret area of anatomy? | 23 |
| Secret attachment, for short | 28 |
| Secret business associate | 25 |
| Secret Chinese society | 22 |
| Secret communication location | 29 |
| Secret couple, in gossip | 24 |
| Secret couple, to Barrett | 25 |
| Secret decoder ring?: Abbr. | 28 |