| Itty | 4 |
| Itt's creator, for short | 28 |
| Itsy-_____ | 10 |
| Itsy-___ | 8 |
| Itsy-__ | 7 |
| Itsy-bitsy yellow garment of song | 33 |
| Itsy-bitsy thing | 16 |
| Itsy-bitsy skirt | 16 |
| Itsy-bitsy piece | 16 |
| Itsy-bitsy hole | 15 |
| Itsy-bitsy door decoration? | 27 |
| Itsy-bitsy critter | 18 |
| Itsy-bitsy creature | 19 |
| Itsy-bitsy bug | 14 |
| Itsy-bitsy bits | 15 |
| Itsy-bitsy biters | 17 |
| Itsy-bitsy biter | 16 |
| Itsy-bitsy bite | 15 |
| Itsy-bitsy bit | 14 |
| Itsy-bitsy amount | 17 |
| Itsy-bitsy | 10 |
| Itsy's partner | 18 |
| Itsy bitsy critter in a kiddie song | 35 |
| Itsy bitsy bit | 14 |
| Itsy bits | 9 |
| Itsy bit | 8 |
| Itself: Lat. | 12 |
| Itself, in a legal phrase | 25 |
| Itself, in a Latin phrase | 25 |
| Itself, in a Latin legal phrase | 31 |
| Its: Fr. | 8 |
| Its, to Irène | 16 |
| Its, in Paris | 13 |
| Its, in France | 14 |
| Its ZIP codes start 89-: Abbr. | 30 |
| Its youngest British member, Elise Tan Roberts, was admitted at age 2 | 69 |
| Its young are called crias | 26 |
| Its yolk is used in mayonnaise | 30 |
| Its yearbook is called the "Gumbo" | 44 |
| Its Yankee Clipper service began in 1939 | 40 |
| Its workers aren't behind closed doors | 42 |
| Its work is picking up | 22 |
| Its work is done in stages | 26 |
| Its work is decreasing? | 23 |
| Its work is decreasing | 22 |
| Its women's basketball team holds the consecutive victories record(abbr.) | 77 |
| Its winner raises the claret jug | 32 |
| Its winner beats the loser with a stick | 39 |
| Its white variety glows upon exposure to oxygen | 47 |
| Its whereabouts are a secret | 28 |
| Its Westwood Replacement Hospital was designed by I.M. Pei | 58 |
| Its website has lesson plans, briefly | 37 |
| Its website has a Neurology Archives page | 41 |
| Its website has a Flag Education page | 37 |
| Its website has a "Rodents 101" section | 49 |
| Its Web site has an Ozone Resource Page | 39 |
| Its Web site has an "Improve Your Game" page | 54 |
| Its Web site has a Swim, Sports & Play page | 47 |
| Its Web site has a Back to School Central page | 46 |
| Its Web site has a "Where's my refund?" page | 58 |
| Its walls withstand pressure | 28 |
| Its walls withstand a lot of pressure | 37 |
| Its volume was 450 000 cubits | 29 |
| Its Vol. XVI is "Soot-Styx" | 37 |
| Its very existence is an open-and-shut case | 43 |
| Its verbal section has a 30-min. time limit | 43 |
| Its vehicles aren't UFOs | 28 |
| Its valve may be bypassed | 25 |
| Its value is in creasing | 24 |
| Its valley is fabled in song | 28 |
| Its valley is dotted with châteaux | 37 |
| Its user can't change it | 28 |
| Its usefulness goes to waste | 28 |
| Its use might leave you out of gas | 34 |
| Its USA Web site Online Assistant is named Anna | 47 |
| Its unique bites are referred to as "breakfast, lunch, and dinner" | 76 |
| Its uniform includes pin-striped trousers | 41 |
| Its uniform includes a red serge tunic and a Stetson: Abbr. | 59 |
| Its U2 edition is black and red | 31 |
| Its two sides are the same | 26 |
| Its two halves usually aren't the same length | 49 |
| Its two halves can't run simultaneously | 43 |
| Its tune is also used for "My Country, 'Tis of Thee" | 66 |
| Its troubles inspired the Sarbanes-Oxley Act | 44 |
| Its trill opens "Rhapsody in Blue" | 44 |
| Its trains service ORD | 22 |
| Its tower was intended to reach Heaven | 38 |
| Its tower tilts | 15 |
| Its title might start with "To" | 41 |
| Its title means "Farewell to Thee" | 44 |
| Its title character is Manrico | 30 |
| Its title character is an opera singer | 38 |
| Its tip may be felt | 19 |
| Its ticker symbol on the NYSE is X | 34 |
| Its three strings are plucked with a bachi | 42 |
| Its three largest cities start with C | 37 |
| Its three largest cities all start with C | 41 |
| Its third verse begins "Let music swell the breeze" | 61 |
| Its third Mon. is when the Boston Marathon is held | 50 |
| Its third edition is scheduled to be finished in 2037: Abbr. | 60 |