| Big initials in news | 20 |
| Big initials in industrial music | 32 |
| Big initials in home shopping | 29 |
| Big initials in fashion | 23 |
| Big initials in Detroit | 23 |
| Big initials in conspiracy theories | 35 |
| Big initials in comedy syndication | 34 |
| Big initials in bowling | 23 |
| Big initials in '70s TV | 27 |
| Big initials at Indy | 20 |
| Big initials among camping enthusiasts | 38 |
| Big influence on Rosie | 22 |
| Big Indy racing family name | 27 |
| Big Indy inits. | 15 |
| Big Indy 500 advertiser | 23 |
| Big Indonesian tourist destination | 34 |
| Big Indonesian export | 21 |
| Big Indians | 11 |
| Big Indian | 10 |
| Big inconveniences | 18 |
| Big inconvenience | 17 |
| Big in the NCAA | 15 |
| Big impression | 14 |
| Big imbiber | 11 |
| Big IMAX feature | 16 |
| Big ice sheet | 13 |
| Big ice chunk | 13 |
| Big I.R.S. mo. | 14 |
| Big I's? | 12 |
| Big I's | 11 |
| Big hurricane of 2011 | 21 |
| Big hurricane of 1966 | 21 |
| Big hunk of time | 16 |
| Big hunk of meat, e.g. | 22 |
| Big hunk | 8 |
| Big human bone | 14 |
| Big hullabaloo | 14 |
| Big huff? | 9 |
| Big houses | 10 |
| Big house? | 10 |
| Big house, so to speak | 22 |
| Big house's rooms | 21 |
| Big house that's not as big? | 32 |
| Big house residents | 19 |
| Big house resident | 18 |
| Big house man or woman | 22 |
| Big house locale | 16 |
| Big house in London | 19 |
| Big house in England | 20 |
| Big house in Britain | 20 |
| Big house in Bloomsbury? | 24 |
| Big house | 9 |
| Big horns | 9 |
| Big horn in mating season | 26 |
| Big horn | 8 |
| Big hoppers, for short | 22 |
| Big hoopla | 10 |
| Big hooha | 9 |
| Big honor for a college athlete | 31 |
| Big honkers | 11 |
| Big honeymoon destination | 25 |
| Big honey brand | 15 |
| Big honcho | 10 |
| Big home run hitter, in slang | 29 |
| Big Hollywood talent agency | 27 |
| Big Hollywood talent agcy. | 26 |
| Big holiday mo. | 15 |
| Big hole | 8 |
| Big holding in Risk | 19 |
| Big holders for coffee | 22 |
| Big HMO provider | 16 |
| Big hits: Abbr. | 15 |
| Big hits, for short | 19 |
| Big hits of a sort | 18 |
| Big hits | 8 |
| Big hit? | 8 |
| Big hit, in Variety slang | 25 |
| Big hit, in slang | 17 |
| Big hit with video gamers | 25 |
| Big hit on the lecture circuit | 30 |
| Big hit on Broadway | 19 |
| Big hit indicator | 17 |
| Big hit in the comics | 21 |
| Big hit in baseball | 19 |
| Big hit from Sting's "Brand New Day" album | 56 |
| Big hit for the club members, and what might elicit the shaded words | 68 |
| Big hit for The Beach Boys | 26 |
| Big hit for Janis Joplin | 24 |
| Big hit for Frankie Laine | 25 |
| Big hit for Bobby Day, back in the day | 38 |
| Big hit at birthday parties | 27 |
| Big hit | 7 |
| Big historical periods | 22 |
| Big hirer of techies | 20 |
| Big hikes | 9 |
| Big hike | 8 |
| Big highway rigs | 16 |
| Big highway | 11 |
| Big high-school event | 21 |
| Big high school event | 21 |