| Big pol. campaign donor | 23 |
| Big poker player's wager | 28 |
| Big Poison or Little Poison | 27 |
| Big Poison of baseball | 22 |
| Big poet for java | 17 |
| Big plot | 8 |
| Big player in the Suez Crisis | 29 |
| Big play for an NFL D-back | 26 |
| Big planters | 12 |
| Big planning on Madison Avenue | 30 |
| Big planes | 10 |
| Big plan | 8 |
| Big place in New York | 21 |
| Big place in California | 23 |
| Big place for transit in Venice | 31 |
| Big place for duds | 18 |
| Big place | 9 |
| Big pizzas | 10 |
| Big pix: Abbr. | 14 |
| Big pitcher | 11 |
| Big pitch | 9 |
| Big pistol manufacturer | 23 |
| Big pistol maker | 16 |
| Big pipes | 9 |
| Big pipe | 8 |
| Big pile of cash | 16 |
| Big pile | 8 |
| Big pigs | 8 |
| Big pig | 7 |
| Big pieces of tuna | 18 |
| Big pieces | 10 |
| Big piece of meat loaf | 22 |
| Big piece of lettuce | 20 |
| Big piece of ice | 16 |
| Big piece of crust? | 19 |
| Big piece of cake | 17 |
| Big piece of cabbage | 20 |
| Big piece of artillery | 22 |
| Big piece in a corner office, perhaps | 37 |
| Big piece | 9 |
| Big pictures? | 13 |
| Big pictures: Abbr. | 19 |
| Big pictures | 12 |
| Big picture?: Abbr. | 19 |
| Big picture? | 12 |
| Big picture: Abbr. | 18 |
| Big picture, really | 19 |
| Big picture from the photo lab (abbr.) | 38 |
| Big picture (abbr.) | 19 |
| Big picture | 11 |
| Big pics | 8 |
| Big pickle? | 11 |
| Big pickle producer | 19 |
| Big picker-upper? | 17 |
| Big piano maker | 15 |
| Big Pharma's overseer | 25 |
| Big Pharma's output | 23 |
| Big Pharma regulator | 20 |
| Big Pharma regulating org. | 26 |
| Big pharma name, for short | 26 |
| Big petrol seller | 17 |
| Big pet food brand | 18 |
| Big periods | 11 |
| Big period | 10 |
| Big PC maker | 12 |
| Big payroll service co. | 23 |
| Big payoff bet | 14 |
| Big payoff | 10 |
| Big partygoer? | 14 |
| Big party: Abbr. | 16 |
| Big party for jalopy owners? | 28 |
| Big party bottles | 17 |
| Big party assessment? | 21 |
| Big party | 9 |
| Big parties | 11 |
| Big part of the Sicilian scenery | 32 |
| Big part of the dairy business? | 31 |
| Big part of many a family budget | 32 |
| Big part of magazine income | 27 |
| Big part of California? | 23 |
| Big part of an order | 20 |
| Big part of an Obama caricature? | 32 |
| Big part of an elephant | 23 |
| Big part of a trucker's budget | 34 |
| Big part of a hare | 18 |
| Big part of a grade, often | 26 |
| Big part of a grade | 19 |
| Big part of a dinosaur skeleton | 31 |
| Big part of a crocodile | 23 |
| Big part | 8 |
| Big parrots | 11 |
| Big parrot | 10 |
| Big parade organizer | 20 |
| Big Papi's team, on scoreboards | 35 |
| Big Papi's team | 19 |
| Big Papi | 8 |
| Big paperback publisher | 23 |
| Big paper, for short | 20 |
| Big pane | 8 |
| Big pan | 7 |