| Mehitabel's creator | 23 |
| Mehitabel's companion | 25 |
| Mehitabel's chronicler | 26 |
| Meh | 3 |
| Megyn Kelly's channel | 25 |
| Megs aplenty | 12 |
| Megillah book | 13 |
| Meghan Daum piece, e.g. | 23 |
| Meghalaya's capital | 23 |
| Megaupload pursuers | 19 |
| Megaton material | 16 |
| Megastore descriptor | 20 |
| Megastars | 9 |
| Megastar | 8 |
| Megaquantities | 14 |
| Megaproportioned | 16 |
| Megaplex count | 14 |
| Megaphone-shaped | 16 |
| Megaphone for a ghost? | 22 |
| Megaphone and soapbox, e.g.? | 28 |
| Megan's "Will & Grace" role | 45 |
| Megan or Michael J. | 19 |
| Megan of "Will & Grace" | 37 |
| Megamistake | 11 |
| Megalopolis with about 30 million people, for short | 51 |
| Megalomaniacal feature | 22 |
| Megalomaniacal captain | 22 |
| Megalomaniac, e.g. | 18 |
| Megalomaniac's problem | 26 |
| Megalomaniac's desire | 25 |
| Megalomania? | 12 |
| Megaliths site in the Pacific | 29 |
| Megalithic monument | 19 |
| Megahit TV series | 17 |
| Megahit by Johnnie Ray | 22 |
| Megahit | 7 |
| Megagram | 8 |
| Megagametophyte containers | 26 |
| Megaflop | 8 |
| Megaera, Tisiphone, and Alecto, collectively | 44 |
| Megadyne fractions | 18 |
| Megadeth: "___, So Good ... So What!" | 47 |
| Megadeth: "The Holy Wars ... The Punishment ___" | 58 |
| Megadeth's Mustaine | 23 |
| Megadeth's music genre | 26 |
| Megadeth's genre | 20 |
| Megadeth song about fibber? | 27 |
| Megadeth "___ Writings" | 33 |
| Megadeth "___ Le Monde" | 33 |
| Megacorporation | 15 |
| Megacomputer sci-fi film | 24 |
| Megacompany who hired a spokesdude named Steven | 47 |
| Megachurch's setting, perhaps | 33 |
| Megacelebrity | 13 |
| Megabucks event? | 16 |
| Megabucks amount, for short | 27 |
| Megabucks | 9 |
| Mega-selling vocalist | 21 |
| Mega-selling singing family | 27 |
| Mega-screen film format | 23 |
| Mega-retailer based in Minneapolis | 34 |
| Mega-quantity, low-quality computer apps | 40 |
| Mega-marathon? | 14 |
| Mega-hit? | 9 |
| Mega-depressing Vietnamese-American model Tequila | 49 |
| Mega-celebrity | 14 |
| Mega-bucks man | 14 |
| Mega-bites? | 11 |
| Mega- times a million | 21 |
| Mega- squared | 13 |
| Mega- or giga- ending | 21 |
| Mega trailer | 12 |
| Mega times 1,024 | 16 |
| Mega Society members have extremely high ones | 45 |
| Mega quantities | 15 |
| Mega or giga attachment | 23 |
| Mega Millions, e.g. | 19 |
| Mega Millions drawing time | 26 |
| Mega Men retailer | 17 |
| Mega celebrity | 14 |
| Mega Bloks competitor | 21 |
| MEGA Bloks alternative | 22 |
| Mega add-on | 11 |
| Meg, the actress | 16 |
| Meg, Jo, Beth and Amy, e.g. | 27 |
| Meg, Jo, Beth and Amy | 21 |
| Meg, among the "Little Women" | 39 |
| Meg's sister sidekick | 25 |
| Meg's mom, on "Family Guy" | 40 |
| Meg's "You've Got Mail" co-star | 49 |
| Meg's "Sleepless in Seattle" role | 47 |
| Meg's "Prelude to a Kiss" costar | 46 |
| Meg's "Prelude to a Kiss" co-star | 47 |
| Meg's ''You've Got Mail'' director | 58 |
| Meg's ''Prelude to a Kiss'' co-star | 55 |
| Meg Ryan's repeated shout in a famous "When Harry Met Sally ..." scene | 84 |
| Meg Ryan remake of 1988 | 23 |
| Meg Ryan ex | 11 |
| Meg or Nolan | 12 |
| Meg or Beth, in literature | 26 |