| It's under pressure | 23 |
| It's under Tenn. | 20 |
| It's under the boardwalk | 28 |
| It's under the conjunctiva | 30 |
| It's under the Host | 23 |
| It's under the Pont Neuf | 28 |
| It's under the Ponte Vecchio | 32 |
| It's under the roof | 23 |
| It's under Wayne Manor | 26 |
| It's under wraps | 20 |
| It's underfoot | 18 |
| It's underfoot! | 19 |
| It's underground | 20 |
| It's undeveloped | 20 |
| It's unfair | 15 |
| It's unfathomable | 21 |
| It's unfortunate | 20 |
| It's unhealthy to draw on, briefly | 38 |
| It's unhealthy to hold one | 30 |
| It's unidentified, usually | 30 |
| It's unique | 15 |
| It's universal, in Chinese philosophy | 41 |
| It's unlikely to air on PBS | 31 |
| It's unlikely to be realized | 32 |
| It's unlikely to be shot on a lot | 37 |
| It's unlikely to make a chicken move | 40 |
| It's unlikely to work | 25 |
| It's unlikely to yield results | 34 |
| It's unmetered | 18 |
| It's unpleasant to be in | 28 |
| It's unpleasant to end on one | 33 |
| It's unpleasant when things end on one | 42 |
| It's unreal | 15 |
| It's unresolved | 19 |
| It's unsettling to be out of them | 37 |
| It's unsmelted | 18 |
| It's untidy | 15 |
| It's unvarnished | 20 |
| It's up all night at camp | 29 |
| It's up all night at camp? | 30 |
| It's up for auction | 23 |
| It's up for bid | 19 |
| It's up for discussion | 26 |
| It's up for grabs every six years | 37 |
| It's up for grabs every two years | 37 |
| It's up for grabs on a court | 32 |
| It's up in the air | 22 |
| It's up in the air? | 23 |
| It's up over 1000% since 1960: Abbr. | 40 |
| It's up the coast from Napoli | 33 |
| It's up there | 17 |
| It's up to you | 18 |
| It's up when you're angry | 33 |
| It's up your sleeve | 23 |
| It's uphill all the way | 27 |
| It's uplifting | 18 |
| It's uplifting to a schusser | 32 |
| It's uplifting to a skier | 29 |
| It's upped at times | 23 |
| It's upstream from Luxor | 28 |
| It's urged by NOW | 21 |
| It's used at Gallaudet U. | 29 |
| It's used between periods | 29 |
| It's used but not owned | 27 |
| It's used by many a junior spy | 34 |
| It's used by people who suck | 32 |
| It's used by some who miss the mark? | 40 |
| It's used during an introductory course | 43 |
| It's used every day in America | 34 |
| It's used for a call in Madrid | 34 |
| It's used for a stick-up? | 29 |
| It's used for an afternoon affair | 37 |
| It's used for announcements | 31 |
| It's used for battering | 27 |
| It's used for cleavage | 26 |
| It's used for coasting | 26 |
| It's used for drawing | 25 |
| It's used for emphasis | 26 |
| It's used for good measure | 30 |
| It's used for ID in the U.S. | 32 |
| It's used for interlocking looped stitches | 46 |
| It's used for plotting | 26 |
| It's used for shortening: Abbr. | 35 |
| It's used for shots | 23 |
| It's used for the big game | 30 |
| It's used for the sake of consistency | 41 |
| It's used for tracking shots | 32 |
| It's used for treating burns | 32 |
| It's used for trim | 22 |
| It's used for wrap-ups, clearly | 35 |
| It's used if all else fails | 31 |
| It's used in a box | 22 |
| It's used in a lunar landing | 32 |
| It's used in arm wrestling | 30 |
| It's used in dashes | 23 |
| It's used in dimly lit conditions | 37 |
| It's used in gumbo | 22 |
| It's used in kicking off some events | 40 |
| It's used in making glass | 29 |
| It's used in oral exams | 27 |