| Two sounds in one | 17 |
| Two solid days | 14 |
| Two socks, one hopes | 20 |
| Two socks | 9 |
| Two smackers? | 13 |
| Two slices of a loaf | 20 |
| Two sizes too small | 19 |
| Two sizes above sm. | 19 |
| Two singers | 11 |
| Two silkworms raced and ended in ___ | 36 |
| Two silkworms raced and ended in --- | 37 |
| Two sides of Pascal's triangle | 34 |
| Two sides of a triangle | 23 |
| Two sides in a battle | 21 |
| Two shots, maybe | 16 |
| Two sheets to the wind? | 23 |
| Two sheets to the wind | 22 |
| Two sharp turns | 15 |
| Two shakes, with "a" | 30 |
| Two shakes equivalent | 21 |
| Two shakes | 10 |
| Two Senators (Vt.-Mich.) | 24 |
| Two semesters | 13 |
| Two selfless things | 19 |
| Two seconds of Edgar Bergen during screen test (5) | 50 |
| Two seater, perhaps? | 20 |
| Two seater, often? | 18 |
| Two seater, maybe? | 18 |
| Two scout groups? | 17 |
| Two Scottish rivers | 19 |
| Two score of low, thick lilies? | 31 |
| Two score | 9 |
| Two scoops of ice cream | 23 |
| TWO ROOMS | 9 |
| Two Roman statesmen | 19 |
| Two Roman generals | 18 |
| Two rockers make a "John" sandwich? | 45 |
| Two residents of the Old Man's beard, in a Lear verse | 57 |
| Two reasons to avoid a dog kennel? | 34 |
| Two reals, in days of old | 25 |
| Two Ralph Waldo Emerson collections | 35 |
| Two racing Unsers | 17 |
| Two Queens stadiums | 19 |
| Two quartets? | 13 |
| Two quartets, combined | 22 |
| Two quartets side-by-side | 25 |
| Two quartets combined | 21 |
| Two quartets | 12 |
| Two quarters of an Isthmian city | 32 |
| Two quarters | 12 |
| Two qtrs. | 9 |
| Two PROOFS | 10 |
| Two pro sports teams | 20 |
| Two printed pages | 17 |
| Two Presidents and an actor | 27 |
| Two prepositions in one | 23 |
| Two pounds, roughly | 19 |
| Two pounds, plus | 16 |
| Two pounds, and then some | 25 |
| Two pounds plus | 15 |
| Two pool lengths | 16 |
| Two points? | 11 |
| Two points, maybe | 17 |
| Two points in time? | 19 |
| Two points for any eleven | 25 |
| Two points | 10 |
| Two poets whose orthography is unusual | 38 |
| Two plus one, in Turin | 22 |
| Two plus one, as always | 23 |
| Two pints | 9 |
| Two pills, maybe | 16 |
| Two pills, e.g. | 15 |
| Two pieces of pizza? | 20 |
| Two piece? | 10 |
| Two picture cards, in blackjack | 31 |
| Two picture cards, in a Vegas game | 34 |
| Two pianists, in musicians' argot | 37 |
| Two physicians with contradictory opinions? | 43 |
| Two periods, essentially | 24 |
| Two performers | 14 |
| Two percent alternative | 23 |
| Two per customer, say | 21 |
| Two people Rickrolling at the same time? | 40 |
| Two peas in ___ | 15 |
| Two peas in -- | 14 |
| Two patriots and a historian | 28 |
| Two parts? | 10 |
| Two pairs? | 10 |
| Two pairs that beat king-high | 29 |
| Two pair? | 9 |
| Two pages | 9 |
| Two paces per second, in a march | 32 |
| Two over Paar? | 14 |
| Two out of two | 14 |
| Two out of twenty? | 18 |
| Two out of three, say | 21 |
| Two out of sixty-six? | 21 |
| Two out of nine? | 16 |
| Two out of fifty? | 17 |
| Two out of 100? | 15 |