| Eponym of a Parkinson research center in Phoenix | 48 |
| Eddie Murphy, to "Saturday Night Live" | 48 |
| Edgar Lee Masters's "___ Rutledge" | 48 |
| Ending for "stink" or "buck" | 48 |
| Ending for "buck" or "stink" | 48 |
| Ed who provided the lead voice in "Up" | 48 |
| Explorer who has a monetary unit named after him | 48 |
| Eric who played Hector in "Troy," 2004 | 48 |
| Eric of "The Time Traveler's Wife" | 48 |
| Entertainer nicknamed "The Great Dane" | 48 |
| Eccentric Tom Hanks comedy, with "The" | 48 |
| Elton John tribute rededicated to Princess Diana | 48 |
| Eastern terminus of 3,205-mile-long U.S. Route 6 | 48 |
| Eighteenth-century explorer aboard the Endeavour | 48 |
| Each episode of "Law & Order," say | 48 |
| End of "profit" or "auction" | 48 |
| Era in which Shakespeare wrote most of his plays | 48 |
| Ecuadoran province named for its gold production | 48 |
| East Los Angeles bus line with a sun in its logo | 48 |
| Energy company that filed for bankruptcy in 2001 | 48 |
| Ending for "hatch" or "cook" | 48 |
| Emerson's "Self-Reliance," for one | 48 |
| Emilio of ''The Breakfast Club'' | 48 |
| English college with a recent swine flu outbreak | 48 |
| Ensler who wrote “The Vagina Monologues” | 48 |
| Electrical unit of capacitance whose symbol is F | 48 |
| Ending with "slug" or "song" | 48 |
| Early West Coast punk band, with "the" | 48 |
| Eugene O'Neill's 'The -- Cometh' | 48 |
| Eric who wrote the book for "Spamalot" | 48 |
| Excited answer to "Who wants dessert?" | 48 |
| Ending with "cop" or "hotel" | 48 |
| Eatery with a "Two x Two x Two" option | 48 |
| Eugène ___ (theater of the absurd playwright) | 48 |
| Ending for "alarm" or "bass" | 48 |
| Emmy-winning co-star of "Chicago Hope" | 48 |
| Eric Clapton hit with a seemingly endless chorus | 48 |
| Ethan's portrayer in "Ethan Frome" | 48 |
| Eric Cartman's mom on "South Park" | 48 |
| Ecological Seuss character, with "The" | 48 |
| Exams for wannabe constitutional scholars: Abbr. | 48 |
| E.M. Forster book posthumously published in 1971 | 48 |
| Exam with a Biological Sciences section, briefly | 48 |
| Etheridge who sang "Come to My Window" | 48 |
| Epoch in which grazing mammals became widespread | 48 |
| Earliest-born member of the Cartoon Hall of Fame | 48 |
| Ending for "pay" or "schnoz" | 48 |
| Ending with "pay" or "Motor" | 48 |
| Evidence that establishes the truth of something | 48 |
| Exam with 10 open-response math questions: Abbr. | 48 |
| Early occurrence in "Some Like It Hot" | 48 |
| Event where one may pull over and switch drivers | 48 |
| ELP song about their guru, with "The"? | 48 |
| Ernest Gaines title about racism, read literally | 48 |
| Excavation locale of an ancient Egyptian capital | 48 |
| Edward James Olmos's directorial debut, 1992 | 48 |
| Elizabeth Taylor was its Founding Intl. Chairman | 48 |
| Eddie's "Coming to America" costar | 48 |
| Emmy winner for "Tuesdays With Morrie" | 48 |
| ESPN anchor known for conferring silly nicknames | 48 |
| Evidence of longshoremen without antiperspirant? | 48 |
| Entertainer known as "The Entertainer" | 48 |
| Exonerate a claimant to his parents' estate? | 48 |
| Epithet for President Bush, with "the" | 48 |
| E. E. Smith cousin of "I Am a Camera"? | 48 |
| Embattled dictator who resigned in January, 1959 | 48 |
| Enthusiastic enjoyment of one's unhappiness? | 48 |
| Ex-"Entertainment Tonight" co-host Bob | 48 |
| Early TV vehicle for Jennifer Lopez, as a dancer | 48 |
| Errol Flynn portrayer in "The Aviator" | 48 |
| Elvis's first feature film, or a 1956 #1 hit | 48 |
| Eliza in "Uncle Tom's Cabin," e.g. | 48 |
| Ending for "sight" or "over" | 48 |
| Erstwhile Secretary of Health and Human Services | 48 |
| Either "Lady and the Tramp" antagonist | 48 |
| Extra-light tennis product made from mattresses? | 48 |
| Essayist to whom the quote is usually attributed | 48 |
| Editor's "it's fine after all" | 48 |
| End of the Lewis and Clark Expedition, 9/23/1806 | 48 |
| Explanation for what happened at Chappaquiddick? | 48 |
| Ernest Hemingway's tale of an Arctic sailor? | 48 |
| Early vehicle for Brad Pitt, as a hot hitchhiker | 48 |
| Eerie sci-fi series, and this puzzle's title | 48 |
| Eight of their names are featured in this puzzle | 48 |
| Exchanges for something of equal value, casually | 48 |
| Equivalent of a pitcher's nod to the catcher | 48 |
| Emma's portrayer in "The Avengers" | 48 |
| Ethan's co-star in "Gattaca," 1997 | 48 |
| Extreme skateboarder who shreds on the halfpipe? | 48 |
| Eustacia of "The Return of the Native" | 48 |
| Emmitt Smith ran for 18,355 in his career: Abbr. | 48 |
| Elgar’s “Symphony No. 1 in ___ Major” | 49 |
| Erstwhile "rubber capital of the world" | 49 |
| Exceptionally intelligent parrot who died in 2007 | 49 |
| Eugene O'Neill's "___ Christie" | 49 |
| Early vehicle for Jeff Goldblum, as a party guest | 49 |
| E.M. Forster classic set in fictional Chandrapore | 49 |
| Everything but the Girl's "Strings" | 49 |
| Element whose name roughly means "lazy" | 49 |
| Elvis's middle name, on his birth certificate | 49 |