| Two-person bike | 15 |
| Two-person basketball game | 26 |
| Two-person bands | 16 |
| Two-person | 10 |
| Two-performer act | 17 |
| Two-percent alternative | 23 |
| Two-passenger carriage | 22 |
| Two-part tile | 13 |
| Two-part lake connected by the Strait of Tiquina | 48 |
| Two-part glue | 13 |
| Two-part glove | 14 |
| Two-part drama that won two Best Play Tonys and a Best Miniseries Emmy | 70 |
| Two-part drama by Shakespeare | 29 |
| Two-part David Bowie song from "Scary Monsters (and Super Creeps)" | 76 |
| Two-part curves | 15 |
| Two-part answer | 15 |
| Two-part | 8 |
| Two-parent households | 21 |
| Two-paneled paintings | 21 |
| Two-palms-down signal | 21 |
| Two-page ads | 12 |
| Two-page ad | 11 |
| Two-outs-in-a-single-AB stats | 29 |
| Two-out actions: Abbr. | 22 |
| Two-Oscar winner Sean | 21 |
| Two-Oscar winner of '91 | 27 |
| Two-Oscar winner Foster | 23 |
| Two-Oscar winner for 1984 | 25 |
| Two-Oscar winner for 1979 | 25 |
| Two-Oscar knight | 16 |
| Two-Oscar Hilary | 16 |
| Two-Oscar actress | 17 |
| Two-Oscar actor who loved crosswords | 36 |
| Two-Oscar actor | 15 |
| Two-of-a-kind vessel | 20 |
| Two-note keyboard effect | 24 |
| Two-note instrument | 19 |
| Two-note announcement | 21 |
| Two-ninths of MMCCLIX | 21 |
| Two-nation peninsula | 20 |
| Two-nation European peninsula | 29 |
| Two-musician ensemble | 21 |
| Two-month-old kid | 17 |
| Two-minute warning giver | 24 |
| Two-mile-high menace | 20 |
| Two-mile-high city | 18 |
| Two-mile-high capital | 21 |
| Two-medium, as some rescues | 27 |
| Two-match link | 14 |
| Two-masters | 11 |
| Two-master | 10 |
| Two-masted vessels | 18 |
| Two-masted vessel | 17 |
| Two-masted ships | 16 |
| Two-masted ship | 15 |
| Two-masted sailing vessels | 26 |
| Two-masted sailing vessel | 25 |
| Two-masted sailing ship | 23 |
| Two-masted sailboats | 20 |
| Two-masted sailboat | 19 |
| Two-masted fore-and-after | 25 |
| Two-masted Dutch fishing vessel | 31 |
| Two-masted craft | 16 |
| Two-masted boats | 16 |
| Two-man test of strength | 24 |
| Two-man competition | 19 |
| Two-man band? | 13 |
| Two-liter bottle contents, sometimes | 36 |
| Two-liter bottle contents | 25 |
| Two-line verse | 14 |
| Two-letter sequence | 19 |
| Two-letter combinations | 23 |
| Two-letter combination | 22 |
| Two-legged zebra | 16 |
| Two-legged wolves' looks | 28 |
| Two-legged wolf's look | 26 |
| Two-legged support | 18 |
| Two-legged stand | 16 |
| Two-legged sponge | 17 |
| Two-legged salamander | 21 |
| Two-legged meat source | 22 |
| Two-legged measuring instruments | 32 |
| Two-legged measuring device | 27 |
| Two-legged measurer | 19 |
| Two-legged livestock | 20 |
| Two-legged creature | 19 |
| Two-legged | 10 |
| Two-layered gem | 15 |
| Two-layered candy | 17 |
| Two-lanes-into-one highway sign | 31 |
| Two-lane topper, often | 22 |
| Two-lane topper | 15 |
| Two-lane highway, maybe | 23 |
| Two-L llama | 11 |
| Two-l creatures | 15 |
| Two-kind link | 13 |
| Two-kind connector | 18 |
| Two-jawed device | 16 |
| Two-inch stripe wearer: Abbr. | 29 |
| Two-inch putt, e.g. | 19 |