| Chemical liquid | 15 |
| Chemical mixture | 16 |
| Chemical moment of truth | 24 |
| Chemical not made since 1995 | 28 |
| Chemical plant graffiti, perhaps | 32 |
| Chemical pollutant | 18 |
| Chemical pollutant, for short | 29 |
| Chemical powder | 15 |
| Chemical prefix | 15 |
| Chemical prefix? | 16 |
| Chemical prefixes | 17 |
| Chemical process also called hyperfiltration | 44 |
| Chemical protein | 16 |
| Chemical radical | 16 |
| Chemical radicals | 17 |
| Chemical reaction phenomenon, and what occurs in four symmetrical pairs of long answers in this puzzle | 102 |
| Chemical reaction portmanteau | 29 |
| Chemical reaction, part 1 | 25 |
| Chemical reaction, part 2 | 25 |
| Chemical reaction, part 3 | 25 |
| Chemical reaction, part 4 | 25 |
| Chemical relative | 17 |
| Chemical restricted by the Stockholm Convention | 47 |
| Chemical salt | 13 |
| Chemical salt in some black inks | 32 |
| Chemical salt in some inks | 26 |
| Chemical salts | 14 |
| Chemical snake | 14 |
| Chemical solid | 14 |
| Chemical solvent | 16 |
| Chemical sprayed on fruit until 1989 | 36 |
| Chemical sprayed on plants | 26 |
| Chemical starter | 16 |
| Chemical substance | 18 |
| Chemical substance that hastens aging | 37 |
| Chemical substance used in a darkroom | 37 |
| Chemical substances | 19 |
| Chemical suffix | 15 |
| Chemical suffix replaced by ide | 31 |
| Chemical suffixes | 17 |
| Chemical sugar | 14 |
| Chemical sugars | 15 |
| Chemical term after poly- | 25 |
| Chemical that keeps the baloney out? | 36 |
| Chemical used as an emollient | 29 |
| Chemical used by document forgers | 33 |
| Chemical used for riot control | 30 |
| Chemical used in anaesthesia | 28 |
| Chemical used in analysis | 25 |
| Chemical used in dyes | 21 |
| Chemical used in fertilizer | 27 |
| Chemical used in film developing | 32 |
| Chemical used in making soap | 28 |
| Chemical used in perfumes | 25 |
| Chemical used to cure animal skins | 34 |
| Chemical used to make biodiesel | 31 |
| Chemical variants | 17 |
| Chemical warfare chemical | 25 |
| Chemical warfare gas | 20 |
| Chemical warfare weapon | 23 |
| Chemical warfare weapons | 24 |
| Chemical washings | 17 |
| Chemical weapon | 15 |
| Chemical weapons | 16 |
| Chemical weapons face protector | 31 |
| Chemical with violet odor | 25 |
| Chemical wood-treating agent? | 29 |
| Chemical ___ | 12 |
| Chemical ___ (nickname for a member of Saddam's inner circle) | 65 |
| Chemical-burn causers | 21 |
| Chemical-compound suffix | 24 |
| Chemical-free | 13 |
| Chemical-free fare | 18 |
| Chemically active substances | 28 |
| Chemically colored in advance | 29 |
| Chemically comatose | 19 |
| Chemically inactive | 19 |
| Chemically inert | 16 |
| Chemically nonreactive | 22 |
| Chemically nonreactive, as a gas | 32 |
| Chemically quiet | 16 |
| Chemically related compound | 27 |
| Chemically related compounds | 28 |
| Chemically similar substances | 29 |
| Chemically treated tresses | 26 |
| Chemically unreactive | 21 |
| Chemically unstable | 19 |
| Chemicals | 9 |
| Chemicals banned by Congress in '76 | 39 |
| Chemicals giant | 15 |
| Chemicals name | 14 |
| Chemin de -- | 12 |
| Chemin de fer | 13 |
| Chemin de fer bettor's declaration | 38 |
| Chemin de fer need | 18 |
| Chemin de __ | 12 |
| Chemin de ___ | 13 |
| Chemin de ___ (card game) | 25 |
| Chemin de ___ (casino card game) | 32 |
| Chemin de ___ (casino game) | 27 |