| Popular sport fish | 18 |
| Popular Sporcle subj. | 21 |
| Popular spicy cuisine | 21 |
| Popular spectator sport that's not in the Olympics | 54 |
| Popular space-saving device | 27 |
| Popular souvenirs | 17 |
| Popular souvenir item | 21 |
| Popular souvenir choice | 23 |
| Popular souvenir | 16 |
| Popular Southern vegetable | 26 |
| Popular Southern breakfast food | 31 |
| Popular South African language group | 36 |
| Popular source of quotes, for short | 35 |
| Popular source of antioxidants | 30 |
| Popular soup or sauce | 21 |
| Popular soup legume | 19 |
| Popular soup ingredient | 23 |
| Popular soup in New England | 27 |
| Popular sort | 12 |
| Popular Sony product | 20 |
| Popular songstress | 18 |
| Popular song with kicks | 23 |
| Popular song subject | 20 |
| Popular song since 1917 | 23 |
| Popular song since 1908 | 23 |
| Popular song of yore | 20 |
| Popular song of yesteryear | 26 |
| Popular song of the '30's | 33 |
| Popular song of 1955 | 20 |
| Popular song of 1926 | 20 |
| Popular song of 1889 | 20 |
| Popular song of '40s | 24 |
| Popular song King | 17 |
| Popular song in the round | 25 |
| Popular song genre on “The Lawrence Welk Show” | 54 |
| Popular song from Broadway's "The Wiz" | 52 |
| Popular song | 12 |
| Popular soft-shoe song | 22 |
| Popular soft-drink flavor | 25 |
| Popular soft drinks | 19 |
| Popular soft drink | 18 |
| Popular sodas | 13 |
| Popular soda | 12 |
| Popular social networking site, and this puzzle's theme | 59 |
| Popular soap opera | 18 |
| Popular soap | 12 |
| Popular snorkeling destination | 30 |
| Popular sneakers | 16 |
| Popular sneaker | 15 |
| Popular snacks that inspired this puzzle's theme | 52 |
| Popular snack since 1912 | 24 |
| Popular snack cracker | 21 |
| Popular snack chip | 18 |
| Popular snack cakes | 19 |
| Popular snack cake | 18 |
| Popular snack brand | 19 |
| Popular snack | 13 |
| Popular smokes | 14 |
| Popular smartphone app | 22 |
| Popular small plane | 19 |
| Popular slogan | 14 |
| Popular sleep aid | 17 |
| Popular sleek-bodied phone | 26 |
| Popular skin moisturizer | 24 |
| Popular skin cream brand | 24 |
| Popular skin cream | 18 |
| Popular skillet spray | 21 |
| Popular skiing destination | 26 |
| Popular ski spot | 16 |
| Popular ski resort | 18 |
| Popular ski country homes | 25 |
| Popular six-second clips since 2013 | 35 |
| Popular site for collectors | 27 |
| Popular sitcom | 14 |
| Popular singing star | 20 |
| Popular singing show, familiarly | 32 |
| Popular singer born in County Donegal | 37 |
| Popular singer | 14 |
| Popular sing-along tune of 1925 | 31 |
| Popular sing-along folk song | 28 |
| Popular signature | 17 |
| Popular sides | 13 |
| Popular side order | 18 |
| Popular side dishes | 19 |
| Popular side dish | 17 |
| Popular side | 12 |
| Popular shrub | 13 |
| Popular show offering | 21 |
| Popular show horses | 19 |
| Popular show | 12 |
| Popular shopping venue | 22 |
| Popular shopping spot | 21 |
| Popular shopping place these days | 33 |
| Popular shopping place | 22 |
| Popular shopping locale | 23 |
| Popular shopping channel | 24 |
| Popular shooter | 15 |
| Popular shoe polish once | 25 |
| Popular shoe brand from Denmark | 31 |
| Popular shirts | 14 |