| One end of the bed | 18 |
| One end of the Alcan Highway | 28 |
| One end of St. George's Channel | 35 |
| One end of some hammers | 23 |
| One end of Ontario's Welland Canal | 38 |
| One end of New York's Triborough Bridge | 43 |
| One end of Manhattan | 20 |
| One end of London | 17 |
| One end of a spectrum | 21 |
| One end of a sock | 17 |
| One end of a radius: Abbr. | 26 |
| One end of a pump | 17 |
| One end of a plunger | 20 |
| One end of a pig | 16 |
| One end of a pencil | 19 |
| One end of a nave | 17 |
| One end of a narthex | 20 |
| One end of a maze | 17 |
| One end of a match: Abbr. | 25 |
| One end of a hub | 16 |
| One end of a homemade walkie-talkie | 35 |
| One end of a hammerhead | 23 |
| One end of a hammer | 19 |
| One end of a gas gauge | 22 |
| One end of a fencing sword | 26 |
| One end of a fallopian tube | 27 |
| One end of a duct | 17 |
| One end of a digression, for short? | 35 |
| One end of a class | 18 |
| One end of a chancel | 20 |
| One end of a canal | 18 |
| One end of a bridge, at times | 29 |
| One end of a bridge | 19 |
| One end of a boar | 17 |
| One end of a battery | 20 |
| One end of a basilica | 21 |
| One encouraging a rapper? | 25 |
| One encouraged to drink on the job | 34 |
| One encountered in a close encounter | 36 |
| One enamored of early Europeans? | 32 |
| One employing trompe l'oeil effects | 39 |
| One employing binoculars | 24 |
| One employed in the Bond trade? | 31 |
| One employed for the summer | 27 |
| One embracing a craze | 21 |
| One eighth of a famous flying team | 34 |
| One egoistically self-absorbed | 30 |
| One edition of the Wall Street Journal | 38 |
| One easily taken in | 19 |
| One easily run over | 19 |
| One easily pushed over | 22 |
| One easily moved | 16 |
| One Earth orbit | 15 |
| One earning rewards | 19 |
| One earning a fee, maybe | 24 |
| One eager to see how the other half lives, say | 46 |
| One eager to compete and defeat | 31 |
| One eager to climb every mountain | 33 |
| One eager for dinner | 20 |
| One E of EEC | 12 |
| One dyne per centimeter measure | 31 |
| One dyeing | 10 |
| One duping | 10 |
| One dunked after school | 23 |
| One drop | 8 |
| One driving too fast | 20 |
| One driving for dough | 21 |
| One driving a car with two brakes, often | 40 |
| One driving a bus.? | 19 |
| One driving | 11 |
| One drinking | 12 |
| One dressing to be noticed | 26 |
| One dressed in white, stereotypically | 37 |
| One dressed in ragged clothes | 29 |
| One dressed in blue | 19 |
| One dressed in black, perhaps | 29 |
| One dressed in black, maybe | 27 |
| One dressed as Vulcan ambassador Sarek, probably | 48 |
| One drawn to igloos | 19 |
| One drawn to hilltops | 21 |
| One drawn to flames | 19 |
| One drawn to a flame | 20 |
| One drawing sympathy | 20 |
| One drawing many blanks | 23 |
| One drawing blood | 17 |
| One drawing a bead | 18 |
| One dragging, maybe | 19 |
| One dozen for Hercules | 22 |
| One down in the mouth | 21 |
| One down in the dumps? | 22 |
| One down in Durango? | 20 |
| One dot over another | 20 |
| One dominated by spirits? | 25 |
| One dollar, in some places | 26 |
| One doing time | 14 |
| One doing the twist, e.g. | 25 |
| One doing the lord's work? | 30 |
| One doing the lord's work | 29 |
| One doing the looking | 21 |
| One doing the hustle | 20 |