| Series of watering troughs? | 27 |
| Series of woes | 14 |
| Series ofskirmishes | 19 |
| Series on a sched. | 18 |
| Series on a ski slope | 21 |
| Series on the WB with the theme song "I'm a Survivor" | 67 |
| Series on which Clint Eastwood played Rowdy Yates | 49 |
| Series opener | 13 |
| Series opener or finale? | 24 |
| Series opener? | 14 |
| Series opening? | 15 |
| Series parts | 12 |
| Series sample | 13 |
| Series season | 13 |
| Series segments | 15 |
| Series set at 328 Chauncey Street in Brooklyn | 45 |
| Series set at Fort Courage | 26 |
| Series set at the Princeton-Plainsboro Teaching Hospital | 56 |
| Series set at the Sterling Cooper Draper Pryce agency | 53 |
| Series set at the Sunshine Cab Company | 38 |
| Series set in an Ohio high school | 33 |
| Series set in DC | 16 |
| Series set in Las Vegas | 23 |
| Series set in So. Cal. | 22 |
| Series set in the California town of Agrestic | 45 |
| Series set on a cruise ship | 27 |
| Series set on a mysterious island | 33 |
| Series shortener | 16 |
| Series shower | 13 |
| Series shutout | 14 |
| Series staged at 30 Rock | 24 |
| Series standout, briefly | 24 |
| Series start | 12 |
| Series starter | 14 |
| Series starter in Santiago | 26 |
| Series tag | 10 |
| Series terminal | 15 |
| Series terminal, briefly | 24 |
| Series termination | 18 |
| Series test | 11 |
| Series that aired its final episode in May 2010 | 47 |
| Series that had 2007 crossover episodes with "CSI" | 60 |
| Series that replaced "Hill Street Blues" | 50 |
| Series unit | 11 |
| Series units | 12 |
| Series VIP | 10 |
| Series whose title character works for Mode magazine | 52 |
| Series winners in 1934 | 22 |
| Series winners: 1969 and 1986 | 29 |
| Series with "Duck Amuck" and "One Froggy Evening" | 69 |
| Series with a "Secrets of the Sun" episode | 52 |
| Series with a Dey in court | 26 |
| Series with an upcoming Episode VII | 35 |
| Series with Capt. Picard, to fans | 33 |
| Series with detective Mac Taylor | 32 |
| Series with lots of homicides | 29 |
| Series with multiple timelines | 30 |
| Series with Sergeant Friday | 27 |
| Series with Smits and Dey | 25 |
| Series' test episode | 24 |
| Series, in Sevilla | 18 |
| Series-concluding abbr. | 23 |
| Series-curtailing abbr. | 23 |
| Series-ending abbr. | 19 |
| Series-long story line | 22 |
| Series-shortening abbr. | 23 |
| Serif or souci preceder | 23 |
| Serif-free character | 20 |
| Serif-free font | 15 |
| Serigraph | 9 |
| Serin | 5 |
| Serio-comic show | 16 |
| Seriocomic show | 15 |
| Serious | 7 |
| Serious about | 13 |
| Serious accident | 16 |
| Serious ailment | 15 |
| Serious alarm | 13 |
| Serious and kind of scary | 25 |
| Serious apprehension | 20 |
| Serious argument components | 27 |
| Serious attention | 17 |
| Serious bacteria | 16 |
| Serious biker's machine | 27 |
| Serious borders? | 16 |
| Serious Broadway fare | 21 |
| Serious ceremonies | 18 |
| Serious ceremony | 16 |
| Serious conflict | 16 |
| Serious conflicts | 17 |
| Serious crime | 13 |
| Serious crimes | 14 |
| Serious criminal | 16 |
| Serious custom | 14 |
| Serious cut | 11 |
| Serious danger | 14 |
| Serious dating, in personal ads | 31 |
| Serious demeanor | 16 |
| Serious depression | 18 |
| Serious discussion's lack | 29 |