| Essential | 9 |
| Essential acid | 14 |
| Essential acid type | 19 |
| Essential acid, familiarly | 26 |
| Essential acids | 15 |
| Essential amino acid | 20 |
| Essential attribute | 19 |
| Essential attributes | 20 |
| Essential beginning? | 20 |
| Essential being | 15 |
| Essential cell comp. | 20 |
| Essential cell strand | 21 |
| Essential code | 14 |
| Essential commodity | 19 |
| Essential company figure | 24 |
| Essential component | 19 |
| Essential content | 17 |
| Essential element | 17 |
| Essential element of dot-com transactions | 41 |
| Essential facts | 15 |
| Essential feature | 17 |
| Essential flower oil | 20 |
| Essential for an investigator | 29 |
| Essential ingredient | 20 |
| Essential item | 14 |
| Essential items | 15 |
| Essential key | 13 |
| Essential legume in a porridge served hot, cold, or in the pot nine days old | 76 |
| Essential meaning | 17 |
| Essential mineral | 17 |
| Essential nature: L. | 20 |
| Essential nutrient | 18 |
| Essential oil | 13 |
| Essential oil from flowers | 26 |
| Essential oil from flowers (Var.) | 33 |
| Essential oil from petals | 25 |
| Essential oils | 14 |
| Essential or crude substance | 28 |
| Essential organs | 16 |
| Essential part | 14 |
| Essential part of a dog's diet? | 35 |
| Essential part of a grand tour | 30 |
| Essential part of Caesar dressing? | 34 |
| Essential parts | 15 |
| Essential point | 15 |
| Essential points | 16 |
| Essential quality | 17 |
| Essential RNA component | 23 |
| Essential self | 14 |
| Essential seminar for the thrifty? | 34 |
| Essential state | 15 |
| Essential strength | 18 |
| Essential survival skill in a slasher film? | 43 |
| Essential thing | 15 |
| Essential things | 16 |
| Essential to life | 17 |
| Essential type of acid | 22 |
| Essential __ acids | 18 |
| Essential ___ acid | 18 |
| Essential ___ acids | 19 |
| Essential: abbr. | 16 |
| Essentially | 11 |
| Essentially amount (to) | 23 |
| Essentially belongs | 19 |
| Essentially fat-free | 20 |
| Essentially teach opinionated composer (6) | 42 |
| Essentials | 10 |
| Essentials for wannabe nightclub performers? | 44 |
| Essentials ___ (freebie for delayed travelers) | 46 |
| Essentials, and title of this puzzle | 36 |
| Esses' preceders | 20 |
| Essex competitor | 16 |
| Essex contemporaries | 20 |
| Essex contemporary | 18 |
| Essex elevator | 14 |
| Essex exclamation | 17 |
| Essex lover | 11 |
| Essex neighbor | 14 |
| Essex or Duesenberg, memorably | 30 |
| Essex or Edsel | 14 |
| Essex or Hudson | 15 |
| Essex or Mercer | 15 |
| Essex or Monarch | 16 |
| Essex or Nash | 13 |
| Essex resort | 12 |
| Essex's title | 17 |
| Essex, for example | 18 |
| Essex, Oakland, etc. | 20 |
| Essman of "Curb Your Enthusiasm" | 42 |
| Esso ad phrase | 14 |
| Esso competitor | 15 |
| Esso gasoline slogan: "Put a ___" | 43 |
| Esso offerings | 14 |
| Esso product | 12 |
| Esso's critter | 18 |
| Est Est Est, e.g. | 17 |
| Est founder Werner __ | 21 |
| Est originator | 14 |
| EST part: Abbr. | 15 |
| EST word | 8 |