| Up-front money, as for a car | 28 |
| Up-front part of a shoe | 23 |
| Up-front poker payment | 22 |
| Up-front spot at the Met | 24 |
| Up-front theater locale | 23 |
| Up-in-the-air guess: Abbr. | 26 |
| Up-tempo Caribbean dance | 24 |
| Up-tempo jazz piano style | 25 |
| Up-to-date "Great!" | 29 |
| Up-to-date actor Carney? | 24 |
| Up-to-date, for Bruce? | 22 |
| Up-to-date, informally | 22 |
| Upbeat Glenn Miller classic? | 28 |
| Upcoming graduates: Abbr. | 25 |
| Upcoming James Cameron film | 27 |
| Upcoming Tampa conventioneers | 29 |
| Update a computer file | 22 |
| Update cartographically | 23 |
| Update military equipment | 25 |
| Update the alarm system | 23 |
| Update the cartography | 22 |
| Update the factory equipment | 28 |
| Update, as a road atlas | 23 |
| Update, as cartography | 22 |
| Update, as factory equipment | 28 |
| Update, as for an atlas | 23 |
| Update, as the bathroom | 23 |
| Update, industrially speaking | 29 |
| Updated 'groovy' | 24 |
| Updated midflight nos. | 22 |
| Updates a factory's gear | 28 |
| Updates a wiki page, say | 24 |
| Updates an electrical system | 28 |
| Updates current carriers | 24 |
| Updates factory machinery | 25 |
| Updike's Harry Angstrom | 27 |
| Updo or ponytail, e.g. | 22 |
| Upfront poker payments | 22 |
| Upgrade electrical systems | 26 |
| Upgrade from a tropical storm | 29 |
| Upgrade from coach, often | 25 |
| Upgrade one's alarm | 23 |
| Upgrade to five stars, say | 26 |
| Upholstered chair insert | 24 |
| Upholstered instrument? | 23 |
| Upholstered piece, often | 24 |
| Upholstered semicircular seat | 29 |
| Upholsterer's choice | 24 |
| Upholsterer's fabrics | 25 |
| Upholsterer's inventory | 27 |
| Upholsterer's meas. | 23 |
| Upholsterer's sample | 24 |
| Upholsterer's target | 24 |
| Upholsterer's tool | 22 |
| Upholsterer's tools | 23 |
| Upholsterers' nails | 23 |
| Upholstery cloth: Var. | 22 |
| Upholstery fabric option | 24 |
| Uplift for some batters | 23 |
| Uplifting enlightenment | 23 |
| Uplifting sight for boaters? | 28 |
| Uplifting sight for ships? | 26 |
| Uplifting undergarment | 22 |
| Uplifts, intellectually | 23 |
| UPN sitcom cancelled in 2001 | 28 |
| Upon quick examination | 22 |
| Upon sitting down to eat? | 25 |
| Upon the Mediterranean | 22 |
| Upon which legions marched | 26 |
| Upper --- (now Burkina Faso) | 28 |
| Upper arm muscle, informally | 28 |
| Upper atmosphere layer | 22 |
| Upper atmosphere protection? | 28 |
| Upper atmospheric layer | 23 |
| Upper back muscle, for short | 28 |
| Upper body strengthener | 23 |
| Upper chamber member: Abbr. | 27 |
| Upper chambers of the heart | 27 |
| Upper class, so to speak | 24 |
| Upper crust of the N.B.A.? | 26 |
| Upper East Side NYC eatery | 26 |
| Upper edge of a hollow object | 29 |
| Upper House member (Abbr.) | 26 |
| Upper house member, briefly | 27 |
| Upper house member: Abbr. | 25 |
| Upper house members: Abbr. | 26 |
| Upper house of le Parlement | 27 |
| Upper left-hand corner key | 26 |
| Upper limit, for short | 22 |
| Upper limit, informally | 23 |
| Upper management, loosely | 25 |
| Upper Midwest's -- Canals | 29 |
| Upper New York Bay island | 25 |
| Upper or lower follower | 23 |
| Upper or lower, in New York | 27 |
| Upper part of a glacier | 23 |
| Upper part of a steeple | 23 |
| Upper part of glaciers | 22 |
| Upper part of the foot | 22 |
| Upper parts of piano duets | 26 |