| It's walked on, in an Annie Lennox song | 43 |
| It's usually abbreviated "c." | 43 |
| Intonations from the monastery locker room? | 43 |
| Its two halves can't run simultaneously | 43 |
| It makes a high-pitched noise for attention | 43 |
| Illness transmitted from Little Miss Muffet | 43 |
| It may be raised in a Congressional meeting | 43 |
| It's won by scoring two points in a row | 43 |
| Indian dish made with stewed legumes (Var.) | 43 |
| It joins Chesapeake Bay and Albemarle Sound | 43 |
| It contains arias about air-cushioned soles | 43 |
| Insect honored on a 1999 U.S. postage stamp | 43 |
| Israeli Prime Minister who resigned in 2001 | 43 |
| It's often attached to Christmas lights | 43 |
| It's hard to tear yourself away from it | 43 |
| It may start, "Dear Sir or Madam" | 43 |
| Ingredient in some frighteningly hot sauces | 43 |
| Its banks are lined with nearly 200 palaces | 43 |
| It rates over 100,000 on the Scoville scale | 43 |
| Indulge in some terrible TV masochistically | 43 |
| Indian present at the "Creation"? | 43 |
| It's tested using the scientific method | 43 |
| Irritated reply to 'Are you awake?' | 43 |
| It usually starts "How many ...?" | 43 |
| Items no longer banned on planes by the TSA | 43 |
| It's probably better not to answer this | 43 |
| Ilsa ___ ("Casablanca" character) | 43 |
| It's decisively important to a solution | 43 |
| It's about six months from the dog days | 43 |
| Impressionist's study of a washerwoman? | 43 |
| Inhabitants of central African rain forests | 43 |
| It should be written in the leftmost column | 43 |
| Informal headwear that can't be shared? | 43 |
| It's often the first to be knocked over | 43 |
| It forms a set with Vermont and Connecticut | 43 |
| It's on the left-hand side of a highway | 43 |
| It's rolled with a pin and put in a tin | 43 |
| In the afternoon, in British military slang | 43 |
| It was developed by Apple, IBM and Motorola | 43 |
| It may weigh on a weight lifter's mind? | 43 |
| Island where Napoleon was exiled (and died) | 43 |
| It's used during an introductory course | 43 |
| Improv music popularized by Ella Fitzgerald | 43 |
| It's nearly bisected by the Missouri R. | 43 |
| It's now called "Periodicals" | 43 |
| Increase the appeal of, with "up" | 43 |
| IdaHO's "Niagara of the West" | 43 |
| In billiards, what the English call English | 43 |
| It's often found under a Christmas tree | 43 |
| In other words, it comes in 100 tiny pieces | 43 |
| It's what all the world is, in a saying | 43 |
| Intimidate, in a way, with "down" | 43 |
| Immortal manager nicknamed for his hometown | 43 |
| Instrument bought at Sotheby's, perhaps | 43 |
| It speaks of "delicate pleasures" | 43 |
| It's down, in a Homestar Runner cartoon | 43 |
| Its extract is used in Worcestershire sauce | 43 |
| Isn't likely to win any culinary awards | 43 |
| It could be a heart up someone's sleeve | 43 |
| Impetus for a 1773 Boston "party" | 43 |
| Iron-___ (brand of nutritional supplements) | 43 |
| It's often said before "said" | 43 |
| Indie/electronica group formed in Edinburgh | 43 |
| It's too important to ignore, literally | 43 |
| It could be represented by an "X" | 43 |
| It's needed while watching a tearjerker | 43 |
| It's frequently under a star's name | 43 |
| It's supportive for those eating in bed | 43 |
| It's usually smaller than a city: Abbr. | 43 |
| In other words, it'll break in 24 hours | 43 |
| Its license plates depict the Delicate Arch | 43 |
| It'll tell you which way the wind blows | 43 |
| Instrument popular in Shakespeare's day | 43 |
| It's good for absolutely nothing [hunh] | 43 |
| It's almost always actually horseradish | 43 |
| Instantaneous web-based communication syst. | 43 |
| It precedes Yankee in the phonetic alphabet | 43 |
| It's often posted at a freeway entrance | 43 |
| It's wasted on the young, it's said | 43 |
| It's nice when checks have lots of them | 43 |
| In Boston, this makes a god out of a guard | 42 |
| It's usually said with the eyes closed | 42 |
| It's leading a campaign to close Gitmo | 42 |
| It's what pride goeth before, they say | 42 |
| It might be said ahead of "said" | 42 |
| Irish actor Gillen of "The Wire" | 42 |
| Its State Quarter has Braille on it: Abbr. | 42 |
| It's more than twice the size of Texas | 42 |
| It gained independence from France in 1962 | 42 |
| Its hub is Leonardo da Vinci International | 42 |
| It may accompany waves on a Hawaiian beach | 42 |
| It's about 80 miles east of Pittsburgh | 42 |
| It's lost when one starts getting paid | 42 |
| It may follow "forever and ever" | 42 |
| Independent Presidential candidate of 1980 | 42 |
| Impossibles song "Erin With ___" | 42 |
| It goes before E except after C, sometimes | 42 |
| In respect to, with ''of'' | 42 |
| It can be calculated after taking a survey | 42 |
| Its crew was protected by the goddess Hera | 42 |