| One of the pride of Joy | 23 |
| One of the prexy's staff | 28 |
| One of the Presleys | 19 |
| One of the Prairie Provinces | 28 |
| One of the Power Rangers | 24 |
| One of the Poor Clares | 22 |
| One of the pool ends | 20 |
| One of the pool balls | 21 |
| One of the Ponderosa boys | 25 |
| One of the Poles | 16 |
| One of the Pointer Sisters | 26 |
| One of the Plinys | 17 |
| One of the Pleiades with a month named after her | 48 |
| One of the Pleiades | 19 |
| One of the planets | 18 |
| One of the Planeten | 19 |
| One of the Plain People | 23 |
| One of the plagues | 18 |
| One of the Pirates of Penzance | 30 |
| One of the Pirates | 18 |
| One of the Pine Islands | 23 |
| One of the Pillars of Islam | 27 |
| One of the Pillars of Hercules | 30 |
| One of the phys. sciences | 25 |
| One of the phobias | 18 |
| One of the Philippines | 22 |
| One of the Pharaohs | 19 |
| One of the PGA tours | 20 |
| One of the Petes | 16 |
| One of the pet set | 18 |
| One of the Perons | 17 |
| One of the Pequod's owners | 30 |
| One of the Pep Boys | 19 |
| One of the people responsible for "Spider-Man: Turn Off the Dark" | 75 |
| One of the people conquered by Cyrus | 36 |
| One of the Penns | 16 |
| One of the Pennines | 19 |
| One of the Pelican State natives | 32 |
| One of the Parnassus nine | 25 |
| One of the Parkers | 18 |
| One of the Parcae et al. | 24 |
| One of the Papas | 16 |
| One of the Palins | 17 |
| One of the Palin children | 25 |
| One of the pairs in a dead man's hand | 41 |
| One of the Pac-Man ghosts | 25 |
| One of the Pac-Man characters | 29 |
| One of the Osmonds | 18 |
| One of the Orkneys | 18 |
| One of the Orkney Islands | 25 |
| One of the original top-level domain name endings | 49 |
| One of the original Seven Sisters colleges | 42 |
| One of the original Politburo members | 37 |
| One of the original Not Ready for Prime Time Players | 52 |
| One of the original Mouseketeers | 32 |
| One of the Original Kings of Comedy | 35 |
| One of the original Baby Bells | 30 |
| One of the original 16 HTML Web colors | 38 |
| One of the original 13: Abbr. | 29 |
| One of the original 13 colonies: Abbr. | 38 |
| One of the original 13 colonies | 31 |
| One of the original 13 | 22 |
| One of the original "Charlie's Angels" | 52 |
| One of the orig. Southern Colonies | 34 |
| One of the orig. 13 | 19 |
| One of the Oranges | 18 |
| One of the opposition | 21 |
| One of the only 12 letter words that typists can produce with just the left hand on a standard keyboard | 103 |
| One of the ones waiting in "Waiting for Godot" | 56 |
| One of the Olsen twins | 22 |
| One of the Olsen sisters | 24 |
| One of the oldest materials for roofs | 37 |
| One of the oldest forms of dress | 32 |
| One of the oil companies: Abbr. | 31 |
| One of the official languages of the Northwest Territories | 58 |
| One of the official languages of Pakistan | 41 |
| One of the official languages of India | 38 |
| One of the oceans: Abbr. | 24 |
| One of the Oceanids | 19 |
| One of the Oceanides, in Greek myth | 35 |
| One of the Oceanides | 20 |
| One of the Obamas | 17 |
| One of the Obama girls | 22 |
| One of the Obama daughters | 26 |
| One of the Oasis brothers | 25 |
| One of the O'Neills | 23 |
| One of the North Africans | 25 |
| One of the noble metals | 23 |
| One of the noble gases | 22 |
| One of the Nixons | 17 |
| One of the nitrites | 19 |
| One of the nine Muses | 21 |
| One of the nightshade family | 28 |
| One of the Nielsen brothers | 27 |
| One of the Niagara River's sources | 38 |
| One of the NFL Mannings | 23 |
| One of the news media | 21 |
| One of the newly rich | 21 |
| One of the New Hebrides | 23 |
| One of the networks | 19 |