| One once again | 14 |
| One once at Brown, e.g. | 23 |
| One one's toes | 18 |
| One one-hundredth of a newton | 29 |
| One online | 10 |
| One only in it for the money | 28 |
| One open to baseless charges? | 29 |
| One opening a can of worms? | 27 |
| One opening a jail door, say | 28 |
| One opening a manual | 20 |
| One opening up a can of worms? | 30 |
| One operating a loom | 20 |
| One opinionated to a fault | 26 |
| One opposed | 11 |
| One opposed to empire building | 30 |
| One option for Hamlet | 21 |
| One or 11, in blackjack | 23 |
| One or another | 14 |
| One or eleven | 13 |
| One or eleven in blackjack | 26 |
| One or false | 12 |
| One or more | 11 |
| One or more ancient Egyptian kings | 34 |
| One or more preceder | 20 |
| One or more prefix | 18 |
| One or side | 11 |
| One or some | 11 |
| One or the other | 16 |
| One or thing starter | 20 |
| One or twenty, e.g. | 19 |
| One or two | 10 |
| One or two beverages? | 21 |
| One or two bucks | 16 |
| One or two carriers? | 20 |
| One or two game implements? | 27 |
| One or two of them often make a lot | 35 |
| One or two spreads? | 19 |
| One or two vehicles? | 20 |
| One or two, e.g. | 16 |
| One or two, ironically | 22 |
| One orbit around the sun | 24 |
| One ordered to have a stroke | 28 |
| One ordered to stop? | 20 |
| One ordered to take two tablets | 31 |
| One ornamenting | 15 |
| One out | 7 |
| One out early | 13 |
| One out for a buck? | 19 |
| One out for blood | 17 |
| One out front: Abbr. | 20 |
| One out of 10? | 14 |
| One out of a hundred: abbr. | 27 |
| One out of fashion | 18 |
| One out of his element | 22 |
| One out of prison | 17 |
| One out of ten | 14 |
| One out of the cooler, maybe | 28 |
| One out of three in Iowa: Abbr. | 31 |
| One out of two | 14 |
| One out on a limb | 17 |
| One out on a limb? | 18 |
| One out to right a wrong | 24 |
| One out? | 8 |
| One outwardly powerful, inwardly weak | 37 |
| One over | 8 |
| One over 65, perhaps | 20 |
| One over a birdie | 17 |
| One over due | 12 |
| One over one under | 18 |
| One over par | 12 |
| One over par, in golf | 21 |
| One over par: Var. | 18 |
| One over the limit | 18 |
| One over two | 12 |
| One over you, perhaps | 21 |
| One overacting | 14 |
| One overcoming low self-esteem? | 31 |
| One overly concerned with details | 33 |
| One overly concerned with propriety | 35 |
| One overly modest | 17 |
| One overseas | 12 |
| One overseen by a sgt. | 22 |
| One Pac-Man ghost | 17 |
| One paid for giving a tip | 25 |
| One paid for services rendered? | 31 |
| One paid to act as a go-between | 31 |
| One paid to be a go-between | 27 |
| One paid to be others | 21 |
| One paid to do a balancing act, briefly | 39 |
| One paid to get shot | 20 |
| One paid to help you get a grip? | 32 |
| One paid to make calls | 22 |
| One paid to make hoops, briefly | 31 |
| One paid to play | 16 |
| One paid to take people out? | 28 |
| One parodied on "Portlandia" | 38 |
| One part in a hundred | 21 |
| One part of a flight | 20 |
| One part of a whole | 19 |
| ONE PART OF EMPLOYEE RETURNS TO JOB! | 36 |