| One spotted in an alley | 23 |
| One spotted at the Rodeo Drive Taco Bell? | 41 |
| One sporting three stars: Abbr. | 31 |
| One sporting a blue cap with a white Y | 38 |
| One spooning | 12 |
| One sponsored at a baptism, perhaps | 35 |
| One sponsored at a baptism | 26 |
| One spinning one's wheels? | 30 |
| One spending a long time in the bathroom? | 41 |
| One spending a long time in human resources, likely | 51 |
| One spelling of Elvis's middle name | 39 |
| One spelling for Arabian princes | 32 |
| One spelling for an old Russian ruler | 37 |
| One spelling for an Indian dress | 32 |
| One spelling for an Arab commander | 34 |
| One spelling for a Muslim prince | 32 |
| One spelling for a mideast prince | 33 |
| One spelling for a Hindu princess | 33 |
| One specializing in slugging | 28 |
| One speaking positively | 23 |
| One speaking nonsense | 21 |
| One sparring | 12 |
| One spared in a sacrifice | 25 |
| One spans two words in each answer to a starred clue | 52 |
| One spade, two clubs, etc. | 26 |
| One spade, etc. | 15 |
| One spade | 9 |
| One south of the border | 23 |
| One source of vitamin C | 23 |
| One source of shingles | 22 |
| One source of roe | 17 |
| One source of protein | 21 |
| One source of pleasure | 22 |
| One source of oil | 17 |
| One source of milk | 18 |
| One source of iodine | 20 |
| One source of info | 18 |
| One source of energy | 20 |
| One source of bran | 18 |
| One sound of contentment | 24 |
| One sought for advice | 21 |
| One sort of miss | 16 |
| One soothed by music, perhaps | 29 |
| One soon to be out of service? | 30 |
| One sometimes clay-footed | 25 |
| One sometimes called a cougar | 29 |
| One sometimes affected by a glass ceiling | 41 |
| One solving several crosswords simultaneously? | 46 |
| One Solstice mo. | 16 |
| One sold at Sotheby's in 1989 for more than $50,000 | 55 |
| One sock, to the other | 22 |
| One sock, to another | 20 |
| One socially challenged | 23 |
| One snapping a ball to the QB: Abbr. | 36 |
| One smoothing clothes | 21 |
| One smeared in England | 22 |
| One small step for a man? | 25 |
| One small step | 14 |
| One slowly collecting | 21 |
| One slow to get up | 18 |
| One slow on the uptake | 22 |
| One slightly higher in a tree | 29 |
| One sleeping on a bed of nails, e.g. | 36 |
| One sleeping "in the jungle, the mighty jungle," in song | 66 |
| One slain by Cain | 17 |
| One skipping the middle man | 27 |
| One skipping church? | 20 |
| One skilled with a sickle | 25 |
| One skilled with a harpoon | 26 |
| One skilled in repartee | 23 |
| One skilled in plane talk | 25 |
| One skilled in match play | 25 |
| One skilled in emergency childbirth | 35 |
| One skilled in divination | 25 |
| One skilled in defense | 22 |
| One skilled in debate | 21 |
| One skilled in CPR | 18 |
| One skilled in bell ringing | 27 |
| One skilled at wordplay | 23 |
| One skilled at taking in | 24 |
| One skilled at repartee | 23 |
| One skilled at pulling strings | 30 |
| One skilled at mimicry | 22 |
| One skilled at managing his pride? | 34 |
| One skilled at managing his pride | 33 |
| One skilled at expressing relief? | 33 |
| One skilled at dead reckoning? | 30 |
| One size smaller than English | 29 |
| One sixty-billionth of a min. | 29 |
| One sitting on the stand | 24 |
| One sitting on the porch | 24 |
| One sitting on a nest egg | 25 |
| One sitting in your lap, perhaps | 32 |
| One sitting carelessly | 22 |
| One sip, say | 12 |
| One sip, maybe: Abbr. | 21 |
| One singled out before drinking | 31 |
| One singing in the kitchen | 26 |
| One singing "Those Were the Days"? | 44 |
| One singing "Fight, fight, fight for Maryland!" | 57 |