| Second-highest-grossing film of 2003 | 36 |
| Second-in-command | 17 |
| Second-in-command in a kitchen | 30 |
| Second-in-command in the kitchen | 32 |
| Second-in-command to Captain Kirk | 33 |
| Second-in-command: abbr. | 24 |
| Second-largest Arab emirate in area | 35 |
| Second-largest bird | 19 |
| Second-largest Central American city | 36 |
| Second-largest city in Ark. | 27 |
| Second-largest city in Finland | 30 |
| Second-largest city in Italy | 28 |
| Second-largest city in Kyrgyzstan | 33 |
| Second-largest city in New Hampshire | 36 |
| Second-largest city in Nicaragua | 32 |
| Second-largest city in Oklahoma | 31 |
| Second-largest city in the 46th state | 37 |
| Second-largest city of Italia | 29 |
| Second-largest city of Rhode Island | 35 |
| Second-largest city on the Atlantic coast | 41 |
| Second-largest cont. | 20 |
| Second-largest continent | 24 |
| Second-largest country | 22 |
| Second-largest country in Africa by area | 40 |
| Second-largest deer | 19 |
| Second-largest denomination of Islam | 36 |
| Second-largest existing bird | 28 |
| Second-largest Great Lake | 25 |
| Second-largest Greek island | 27 |
| Second-largest Hawaiian island | 30 |
| Second-largest human bone | 25 |
| Second-largest Indian city | 26 |
| Second-largest Islam denomination | 33 |
| Second-largest island | 21 |
| Second-largest island in the Med. | 33 |
| Second-largest lake in Europe | 29 |
| Second-largest lake in North America | 36 |
| Second-largest land animal | 26 |
| Second-largest land animal, briefly | 35 |
| Second-largest living bird | 26 |
| Second-largest living birds | 27 |
| Second-largest Med. island | 26 |
| Second-largest Mediterranean island | 35 |
| Second-largest moon in the solar system | 39 |
| Second-largest moon of Saturn | 29 |
| Second-largest nation | 21 |
| Second-largest of seven | 23 |
| Second-largest of the Aleutians | 31 |
| Second-largest of the deer family | 33 |
| Second-largest of the Hawaiian islands | 38 |
| Second-largest planet | 21 |
| Second-largest planet in the solar system | 41 |
| Second-largest primarily French-speaking city in the world | 58 |
| Second-largest religion | 23 |
| Second-largest Saturnian moon | 29 |
| Second-largest Siberian city | 28 |
| Second-largest Sri Lankan ethnicity | 35 |
| Second-largest state | 20 |
| Second-largest Syrian city | 26 |
| Second-largest U.S. island in area | 34 |
| Second-largest U.S. stock exchange | 34 |
| Second-largest US island | 24 |
| Second-largest W. Hemisphere country in area | 44 |
| Second-least populous st. capital | 33 |
| Second-level seating | 20 |
| Second-lightest noble gas | 25 |
| Second-longest Bible book | 25 |
| Second-longest human bone | 25 |
| Second-longest Polish river | 27 |
| Second-longest river | 20 |
| Second-longest river of China | 29 |
| Second-lowest poker card | 24 |
| Second-lowest stripe | 20 |
| Second-most common Vietnamese family name, after Nguyen | 55 |
| Second-most populous Arizona city | 33 |
| Second-most populous nation in Afr. | 35 |
| Second-most populous of the United Arab Emirates | 48 |
| Second-most-massive dwarf planet | 32 |
| Second-most-populous country | 28 |
| Second-name preceder | 20 |
| Second-oldest country in the Western Hemisphere | 47 |
| Second-oldest General Mills cereal | 34 |
| Second-oldest member of the Jackson 5 | 37 |
| Second-oldest N.L. stadium | 26 |
| Second-oldest US monthly | 24 |
| Second-oldest US record label | 29 |
| Second-order angel | 18 |
| Second-person person | 20 |
| Second-person pronoun | 21 |
| Second-person singular of ''be'' | 48 |
| Second-place contender | 22 |
| Second-place contestant | 23 |
| Second-place finisher | 21 |
| Second-place finisher's triumph | 35 |
| Second-place finishers | 22 |
| Second-place medals | 19 |
| Second-place Olympic athletes | 29 |
| Second-place prize | 18 |
| Second-qtr. start | 17 |
| Second-qual. | 12 |