| One crossing through the strike zone? | 37 |
| One crouching at home | 21 |
| One Crowder on "Justified" | 36 |
| One crunch, say | 15 |
| One crying 'Boo!' | 25 |
| One crying 'Cut!': Abbr. | 32 |
| One crying foul | 15 |
| One crying uncle? | 17 |
| One Cuban? | 10 |
| One cubic decimeter | 19 |
| One cubic decimetre | 19 |
| One cubic meter | 15 |
| One cuffing | 11 |
| One cup | 7 |
| One cured of a sleep disorder? | 30 |
| One curl or press | 17 |
| One curl or press, e.g. | 23 |
| One curl or push-up | 19 |
| One curl, e.g. | 14 |
| One curl, say | 13 |
| One cursed by Farragut | 22 |
| One cutting locks in airlocks? | 30 |
| One cycle per second | 20 |
| One dancing to "Rakish Paddy" | 39 |
| One dashing to home plate | 25 |
| One daughter of King Lear | 25 |
| One day | 7 |
| One day -- time | 15 |
| One day --- time | 16 |
| One day a week is his | 21 |
| One day at --- | 14 |
| One day at ___ | 14 |
| One day in March | 16 |
| One day ___ time | 16 |
| One Day ____ Time | 17 |
| One day, astronomically | 23 |
| One day: abbr. | 14 |
| One de-creasing | 15 |
| One dealing in futures? | 23 |
| One dealing in red meat for a living? | 37 |
| One dealing with moguls? | 24 |
| One dealing with spirits | 24 |
| One debating the unpopular side | 31 |
| One debuting on "America's Most Wanted"? | 54 |
| One decal to another | 20 |
| One dedicated to the religious life | 35 |
| One deep in thought | 19 |
| One defeated at Châlons in 451 | 33 |
| One definitely not on the run | 29 |
| One defintion of ''can'' | 40 |
| One degree of neatness | 22 |
| One delinquent in delegating | 28 |
| One delivering a panegyric | 26 |
| One delivering the goods | 24 |
| One demonstrating excellent service? | 36 |
| One department of a landscaping company? | 40 |
| One deserving a hand? | 21 |
| One desiring change | 19 |
| One destination from the ER | 27 |
| One destined for baldness? | 26 |
| One destined to pass the bar | 28 |
| One destined to receive | 23 |
| One destined to receive? | 24 |
| One detects an oda here | 23 |
| One determined to lose | 22 |
| One dickering over a price | 26 |
| One difficult task | 18 |
| One difficult to locate | 23 |
| One Direction "Tell Me ___" | 37 |
| One Direction member who named the band (like you know any of the other members) | 80 |
| One Direction singer Styles | 27 |
| One Direction song that references a 1977 Queen anthem | 54 |
| One discharged from the Navy? | 29 |
| One disinclined to do the town | 30 |
| One dismounting from a horse, maybe | 35 |
| One dispatching wise guys to the moon? | 38 |
| One displeasing Santa | 21 |
| One does this with money | 24 |
| One doing a balancing job | 25 |
| One doing a banishing act | 25 |
| One doing a bank job | 20 |
| One doing a con job? | 20 |
| One doing a farm chore | 22 |
| One doing a lot of riding | 25 |
| One doing a pirouette, e.g. | 27 |
| One doing a spot test? | 22 |
| One doing a voice-over | 22 |
| One doing a waggle dance | 24 |
| One doing amniocentesis? | 24 |
| One doing an imitation | 22 |
| One doing blackjack-table arithmetic | 36 |
| One doing body work? | 20 |
| One doing cabinet work? | 23 |
| One doing checks and balances? | 30 |
| One doing clerical work | 23 |
| One doing commercial endorsements, maybe | 40 |
| One doing course work | 21 |
| One doing data entry, probably | 30 |
| One doing dos | 13 |
| One doing drudge work | 21 |