| Cartoon millionaire created by Alfred Harvey | 44 |
| Cartoon millionaire created by Bob Kane | 39 |
| Cartoon millionaire created by Carl Barks | 41 |
| Cartoon millionaire created by Harold Gray | 42 |
| Cartoon mirage | 14 |
| Cartoon mirages | 15 |
| Cartoon monkey | 14 |
| Cartoon moose | 13 |
| Cartoon mouse | 13 |
| Cartoon mouse who "Goes West" | 39 |
| Cartoon Mr. | 11 |
| Cartoon Mutant Ninja | 20 |
| Cartoon myope's surname | 27 |
| Cartoon Network parent co. | 26 |
| Cartoon Network show about a boy named Finn and a dog named Jake | 64 |
| Cartoon Network show that debuted in 1999 | 41 |
| Cartoon Network trio | 20 |
| Cartoon omnivore, familiarly | 28 |
| Cartoon opossum | 15 |
| Cartoon orphan | 14 |
| Cartoon overlays | 16 |
| Cartoon part | 12 |
| Cartoon penguin | 15 |
| Cartoon pet | 11 |
| Cartoon pet of note | 19 |
| Cartoon pic | 11 |
| Cartoon pics | 12 |
| Cartoon pig | 11 |
| Cartoon pioneer Disney | 22 |
| Cartoon pooch | 13 |
| Cartoon possum | 14 |
| Cartoon possum's corporate symbol? | 38 |
| Cartoon private | 15 |
| Cartoon prop, often | 19 |
| Cartoon pup | 11 |
| Cartoon puzzle of newspapers | 28 |
| Cartoon quitting-time shout | 27 |
| Cartoon reporter with a fox terrier named Snowy | 47 |
| Cartoon rooster's name | 26 |
| Cartoon scream | 14 |
| Cartoon sea dweller | 19 |
| Cartoon sea serpent | 19 |
| Cartoon section | 15 |
| Cartoon series | 14 |
| Cartoon series "Speed ___" | 36 |
| Cartoon series about a cave boy | 31 |
| Cartoon series about the Pickles kids | 37 |
| Cartoon set in Colorado | 23 |
| Cartoon shopkeeper | 18 |
| Cartoon show featuring film legend Sophia? | 42 |
| Cartoon show whose theme song is done by Les Claypool of Primus | 63 |
| Cartoon shriek | 14 |
| Cartoon shrieks | 15 |
| Cartoon sign "_____ Joe's" | 40 |
| Cartoon skunk | 13 |
| Cartoon skunk -- La Fume | 24 |
| Cartoon skunk -- Le Pew | 23 |
| Cartoon skunk Le Pew | 20 |
| Cartoon skunk Pepé ___ | 25 |
| Cartoon skunk Pepe | 18 |
| Cartoon skunk ___ Le Pew | 24 |
| Cartoon skunk ___ LePew | 23 |
| Cartoon skunk's first name | 30 |
| Cartoon skunk, to amis | 22 |
| Cartoon sound | 13 |
| Cartoon sound effect | 20 |
| Cartoon spell-caster | 20 |
| Cartoon spun off from "Beavis and Butt-head" | 54 |
| Cartoon spy Natasha | 19 |
| Cartoon squeal | 14 |
| Cartoon squeals | 15 |
| Cartoon squinter | 16 |
| Cartoon stinker | 15 |
| Cartoon storekeeper | 19 |
| Cartoon style | 13 |
| Cartoon superhero | 17 |
| Cartoon superhero dressed in red, white and blue | 48 |
| Cartoon superhero who co-headlined next to Secret Squirrel | 58 |
| Cartoon supplier | 16 |
| Cartoon supplier of anvils and explosive tennis balls | 53 |
| Cartoon supply company | 22 |
| Cartoon sweetheart | 18 |
| Cartoon team | 12 |
| Cartoon tightwad? | 17 |
| Cartoon tot | 11 |
| Cartoon utterance | 17 |
| Cartoon vamp Betty | 18 |
| Cartoon Viking | 14 |
| Cartoon Viking's dog | 24 |
| Cartoon villain | 15 |
| Cartoon villain Badenov | 23 |
| Cartoon villain who sails the Black Barnacle | 44 |
| Cartoon voice Blanc | 19 |
| Cartoon voice star Mel | 22 |
| Cartoon voicer Butler | 21 |
| Cartoon voicer Mel | 18 |
| Cartoon whose guest voices have included Leonard Nimoy, Al Gore and Beck | 72 |
| Cartoon witch | 13 |
| Cartoon woman Olive | 19 |
| Cartoon word said while wincing | 31 |