| Most out of practice | 20 |
| Most otiose | 11 |
| Most ostentatious | 17 |
| Most Oscar-nominated nonwinning actor | 37 |
| Most Oscar presenters | 21 |
| Most ornery | 11 |
| Most original | 13 |
| Most organized | 14 |
| Most orderly | 12 |
| Most or father attachment | 25 |
| Most or all | 11 |
| Most opulent | 12 |
| Most optimistic | 15 |
| Most opportune | 14 |
| Most open | 9 |
| Most on-the-mark | 16 |
| Most on one's guard | 23 |
| Most ominous | 12 |
| Most old-hat | 12 |
| Most offensive | 14 |
| Most offbeat | 12 |
| Most off-the-wall | 17 |
| Most off-tasting | 16 |
| Most off the wall | 17 |
| Most of water | 13 |
| Most of Walton's gear | 25 |
| Most of us have lived in two of them | 36 |
| Most of Uruguay | 15 |
| Most of Turkey is in it | 23 |
| Most of Tom Mix's filmography | 33 |
| Most of them have lines | 23 |
| Most of the world's people | 30 |
| Most of the world's inhabitants | 35 |
| Most of the world | 17 |
| Most of the Western Hemisphere (with "the") | 53 |
| Most of the United Arab Emirates | 32 |
| Most of the U.K. | 16 |
| Most of the time: abbr. | 23 |
| Most of the time | 16 |
| Most of the Ten Commandments, basically | 39 |
| Most of the Sphinx | 18 |
| Most of the kids in a certain kids' game | 44 |
| Most of the Joint Chiefs | 24 |
| Most of the Iberian Peninsula | 29 |
| Most of the globe | 17 |
| Most of the earth's surface | 31 |
| Most of the Earth | 17 |
| Most of the characters on "The West Wing" | 51 |
| Most of the characters in "The Hitchhiker's Guide to the Galaxy" | 78 |
| Most of the atmosphere | 22 |
| Most of the Arctic Ocean | 24 |
| Most of the 1990s, politically | 30 |
| Most of the 101 Dalmatians | 26 |
| Most of the "Happy Days" cast | 39 |
| Most of Switzerland | 19 |
| Most of Santa's mail | 24 |
| Most of Qatar | 13 |
| Most of our globe | 17 |
| Most of Oprah's fans | 24 |
| Most of Ohio's northern boundary | 36 |
| Most of North Africa | 20 |
| Most of Noah's passengers | 29 |
| Most of N.Y. outside N.Y.C. | 27 |
| Most of Mercer's songs | 26 |
| Most of Mauritania | 18 |
| Most of Martha Stewart's sentence | 37 |
| Most of Mali | 12 |
| Most of Libya | 13 |
| Most of Kauai | 13 |
| Most of Jutland | 15 |
| Most of its strains are harmless | 32 |
| Most of its panhandle is in the Pacific Time Zone | 49 |
| Most of its football matches are played on Agar's Plough | 60 |
| Most of it sold in the United States is clarified | 49 |
| Most of it nowadays is filtered | 31 |
| Most of it became a unit of Cal State | 37 |
| Most of Iceland's flag | 26 |
| Most of Iberia | 14 |
| Most of Greenland | 17 |
| Most of George Foreman's wins | 33 |
| Most of galloped | 16 |
| Most of Gabby Hayes's films | 31 |
| Most of earth's surface | 27 |
| Most of Earth | 13 |
| Most of AZ doesn't observe it | 33 |
| Most of AOL | 11 |
| Most of Antarctica | 18 |
| Most of an SOS | 14 |
| Most of an hour? | 16 |
| Most of an alloy | 16 |
| Most of Algeria | 15 |
| Most of a world map | 19 |
| Most of a tooth | 15 |
| Most of a species' evolutionary history | 43 |
| Most of a screenplay | 20 |
| Most of a million? | 18 |
| Most of a googol | 16 |
| Most of a figure eight | 22 |
| Most of a chess set | 19 |
| Most of a 1,000,000,000 | 23 |