| Second Republic of Texas president | 34 |
| Second qtr. start | 17 |
| Second purchase | 15 |
| Second Punic War general | 24 |
| Second printing | 15 |
| Second prime | 12 |
| Second president to be assassinated | 35 |
| Second president of the Weimar Republic | 39 |
| Second president | 16 |
| Second pope, following St. Peter | 32 |
| Second point in tennis | 22 |
| Second point at Wimbledon | 25 |
| Second planet past Merkur | 25 |
| Second planet past Mercur | 25 |
| Second planet from the sun | 26 |
| Second place? | 13 |
| Second place prize | 18 |
| Second place from the right | 27 |
| Second place finisher | 21 |
| Second place award | 18 |
| Second place acknowledgement | 28 |
| Second photographed star | 24 |
| Second photo in some testimonial ads | 36 |
| Second photo in a testimonial ad | 32 |
| Second phones: Abbr. | 20 |
| Second phone: abbr. | 19 |
| Second phase | 12 |
| Second ph. | 10 |
| Second person? | 14 |
| Second person, grammatically | 28 |
| Second person's namesakes | 29 |
| Second person to make a solo transatlantic flight | 49 |
| Second person pronoun | 21 |
| Second person plural, in the South | 34 |
| Second person person | 20 |
| Second person in the Trinity | 28 |
| Second person in the Bible? | 27 |
| Second person in the Bible | 26 |
| Second person in Genesis | 24 |
| Second person copulative | 24 |
| Second person appearing in the Bible | 36 |
| Second person | 13 |
| Second passage: Part VI | 23 |
| Second passage: Part V | 22 |
| Second passage: Part IV | 23 |
| Second passage: Part III | 24 |
| Second passage: Part II | 23 |
| Second part of what's hidden | 32 |
| Second part of the riddle | 25 |
| Second part of the quote | 24 |
| Second part of the quip | 23 |
| Second part of the question | 27 |
| Second part of the message | 26 |
| Second part of the joke | 23 |
| Second part of the headline | 27 |
| Second part of the description | 30 |
| Second part of quote | 20 |
| Second part of assembly instructions, perhaps | 45 |
| Second part of an act | 21 |
| Second part of a three-part command | 35 |
| Second part of a snicker | 24 |
| Second part of a sage thought | 29 |
| Second part of a quip | 21 |
| Second part of a play | 21 |
| Second part of a Latin conjugation | 34 |
| Second part of a kid's game | 31 |
| Second part | 11 |
| Second page in a chapter | 24 |
| Second Oscar/Tony/Emmy/Grammy actress | 37 |
| Second order of angels | 22 |
| Second or third, for instance | 29 |
| Second or third showing, e.g. | 29 |
| Second or third showing | 23 |
| Second or tenth, in a way | 25 |
| Second or sixth president | 25 |
| Second or sixth in a series | 27 |
| Second or human | 15 |
| Second or home | 14 |
| Second or fourth wife of Henry VIII | 35 |
| Second option's lead-in | 27 |
| Second opening? | 15 |
| Second opening in a sock | 24 |
| Second opening | 14 |
| Second only to Bonds in all-time homers | 39 |
| Second offer, as on eBay | 24 |
| Second of two spouses? | 22 |
| Second of two sections | 22 |
| Second of two pieces of fire truck equipment | 44 |
| Second of two photos, perhaps | 29 |
| Second of two mentioned | 23 |
| Second of two groups that may come in handy for this puzzle? | 60 |
| Second of two bell sounds | 25 |
| Second of two | 13 |
| Second of three X's, perhaps | 32 |
| Second of three X's | 23 |
| Second of three words in West Point's motto | 47 |
| Second of three virtues | 23 |
| Second of three kids in actress Charlotte's family? | 55 |
| Second of three black keys | 26 |
| Second of three | 15 |