| Self-enlightenment | 18 |
| Self-employment, as for a doctor or lawyer | 42 |
| Self-employed, as a writer | 26 |
| Self-employed professional | 26 |
| Self-employed person? | 21 |
| Self-employed people? | 21 |
| Self-employed doctor's business | 35 |
| Self-employed detective | 23 |
| Self-employed | 13 |
| Self-effacing response to a compliment | 38 |
| Self-effacing reply to praise | 29 |
| Self-effacing person | 20 |
| Self-effacing people | 20 |
| Self-effacing buccaneer? | 24 |
| Self-effacing | 13 |
| Self-doubting | 13 |
| Self-distributed mag | 20 |
| Self-dismissive remark | 22 |
| Self-discipline | 15 |
| Self-directed Streisand film | 28 |
| Self-directed | 13 |
| Self-diminishing remark | 23 |
| Self-diagnosis? | 15 |
| Self-determining sort | 21 |
| Self-determination | 18 |
| Self-destructive-but-weirdly-more-appealing-for-it type | 55 |
| Self-destruction | 16 |
| Self-destruct | 13 |
| Self-descriptive letters | 24 |
| Self-descriptive fruit | 22 |
| Self-descriptive French name | 28 |
| Self-descriptive crossword answer | 33 |
| Self-described bird watcher, maybe? | 35 |
| Self-described "World's Online Marketplace" | 57 |
| Self-described "short, stocky, slow-witted bald man" of "Seinfeld" | 86 |
| Self-described "saloonkeeper" Toots | 45 |
| Self-described "poor, infirm, weak, and despised old man" of literature | 81 |
| Self-described "Oxford man" of fiction | 48 |
| Self-deprivation | 16 |
| Self-deprecating utterance | 26 |
| Self-deprecating Internet abbreviation | 38 |
| Self-denying one | 16 |
| Self-denying | 12 |
| Self-defense, for one | 21 |
| Self-defense, e.g. | 18 |
| Self-defense with a kick? | 25 |
| Self-defense testifier? | 23 |
| Self-defense technique | 22 |
| Self-defense system | 19 |
| Self-defense study | 18 |
| Self-defense spray | 18 |
| Self-defense sport | 18 |
| Self-defense school | 19 |
| Self-defense overkill? | 22 |
| Self-defense method | 19 |
| Self-defense martial art | 24 |
| Self-defense item | 17 |
| Self-defense art using nonresistance | 36 |
| Self-defense art | 16 |
| Self-defense aid | 16 |
| Self-defeating words | 20 |
| Self-declared | 13 |
| Self-deception | 14 |
| Self-created deity | 18 |
| Self-correcting or self-cleaning, say | 37 |
| Self-correcting circuit | 23 |
| Self-controlled one | 19 |
| Self-controlled | 15 |
| Self-control | 12 |
| Self-contradictory, in a way | 28 |
| Self-contradictory statement | 28 |
| Self-contradictory afterthought | 31 |
| Self-contradictions | 19 |
| Self-contained unit | 19 |
| Self-contained underwater breathing apparatus | 45 |
| Self-contained music equipment | 30 |
| Self-contained module | 21 |
| Self-contained | 14 |
| Self-consoling words | 20 |
| Self-consoling remark | 21 |
| Self-conscious smile | 20 |
| Self-conscious remark when putting on a new outfit | 50 |
| Self-conscious remark when packing too many pounds | 50 |
| Self-conscious question | 23 |
| Self-conscious person's question | 36 |
| Self-conscious laugh | 20 |
| Self-conscious company | 22 |
| Self-conscious | 14 |
| Self-congratulatory statement | 29 |
| Self-congratulatory cry | 23 |
| Self-congratulatory cries | 25 |
| Self-congratulatory comment | 27 |
| Self-congratulatory | 19 |
| Self-congratulated | 18 |
| Self-confident, as a pageant contestant | 39 |
| Self-confident words | 20 |
| Self-confident to a fault | 25 |
| Self-confident declaration | 26 |
| Self-confident composure | 24 |
| Self-confident assertion | 24 |