| Semistable subatomic particle | 29 |
| Semisonic song off "Great Divide" | 43 |
| Semisonic "Great Divide" song (Abbr.) | 47 |
| Semisolid substance | 19 |
| Semisolid material | 18 |
| Semisolid mass | 14 |
| Semisolid lump | 14 |
| Semisolid foods | 15 |
| Semisolid colloids | 18 |
| Semisolid | 9 |
| Semisoft Dutch cheese | 21 |
| Semisoft Danish cheese | 22 |
| Semisoft cheeses | 16 |
| Semisoft cheese with an orange rind | 35 |
| Semisoft cheese from Holland | 28 |
| Semisoft cheese | 15 |
| Semiskilled talker? | 19 |
| Semisheer fabrics | 17 |
| Semisheer fabric | 16 |
| Semis, say | 10 |
| Semis happen near the end of them | 33 |
| Semis | 5 |
| Semirural, say | 14 |
| Semirural region | 16 |
| Semirural commuter | 18 |
| Semirigid colloids | 18 |
| Semirigid colloid | 17 |
| Semiramis's subjects | 24 |
| Semiramis's realm | 21 |
| Semiramis's domain | 22 |
| Semiquincentennial of 9/11 | 26 |
| Semiquavers | 11 |
| Semiquaver, for one | 19 |
| Semiquaver, e.g. | 16 |
| Semipro sports org. whose logo shows a player with a crosse | 59 |
| Semiprivate workspace | 21 |
| Semiprecious stones | 19 |
| Semiprecious stone | 18 |
| Semiprecious gemstone | 21 |
| Semiprecious gem | 16 |
| Semiprecious azure stone | 24 |
| Semipostal, for one | 19 |
| Semiotics study | 15 |
| Semiotician Umberto | 19 |
| Semior citizens | 15 |
| Seminomadic Kenyan | 18 |
| Seminoles' sch. | 19 |
| Seminoles' org. | 19 |
| Seminoles home | 14 |
| Seminole's gridiron rival | 29 |
| Seminole's archrival | 24 |
| Seminole War officer for whom a county was named | 48 |
| Seminole War military post | 26 |
| Seminole War major with counties named after him | 48 |
| Seminole war leader, 1835-37 | 28 |
| Seminole War leader | 19 |
| Seminole st. | 12 |
| Seminole rival, in college sports | 33 |
| Seminole leader | 15 |
| Seminole chief | 14 |
| Seminate anew | 13 |
| Seminary title: Abbr. | 21 |
| Seminary teaching | 17 |
| Seminary subject | 16 |
| Seminary subj. | 14 |
| Seminary study | 14 |
| Seminary official: Abbr. | 24 |
| Seminary heads | 14 |
| Seminary graduate | 17 |
| Seminary grad's degree | 26 |
| Seminary degs. | 14 |
| Seminary degree | 15 |
| Seminary deg. | 13 |
| Seminarian's subj. | 22 |
| Seminar: Abbr. | 14 |
| Seminar session, often (abbr.) | 30 |
| Seminar leaders | 15 |
| Seminar group | 13 |
| Seminar focus | 13 |
| Seminar alternative | 19 |
| Seminar activity | 16 |
| Seminal short-story collection by Asimov | 40 |
| Seminal punk rock label operated by Black Flag | 46 |
| Seminal punk label founded by Black Flag | 40 |
| Seminal punk band, with The | 27 |
| Seminal punk band who took their name from a Paul McCartney pseudonym | 69 |
| Seminal punk band | 17 |
| Seminal parts for a barbershop quartet? | 39 |
| Seminal naturalistic work | 25 |
| Seminal name in science fiction | 31 |
| Seminal mystery of 1887 | 23 |
| Seminal mainframe | 17 |
| Seminal English punk band | 25 |
| Seminal computer game of 1989 | 29 |
| Seminal Chicago industrial label that launched the career of Ministry | 69 |
| Seminal 1962 book on the environment | 36 |
| Semimonthly tides | 17 |
| Semimonthly tide | 16 |
| Semimonthly phenomenon | 22 |
| Semimonthly period, roughly | 27 |