| It takes a year to get around him | 33 |
| It takes a while to tell | 24 |
| It takes a toll: Abbr. | 22 |
| It takes a second to be one | 27 |
| It takes a picture | 18 |
| It takes a pasting | 18 |
| It takes a paddling | 19 |
| It takes a nice drive | 21 |
| It takes a lot to get one upset | 31 |
| It takes a lot of eggs | 22 |
| It takes a light, for short | 27 |
| It takes a licking and keeps on ticking | 39 |
| It takes a licking | 18 |
| It takes a hammering | 20 |
| It takes a few years to mature | 30 |
| It takes a bow in an orchestra | 30 |
| It takes a bow at a recital | 27 |
| It takes a bow at a musical performance | 39 |
| It takes a bow | 14 |
| It takes a big bow | 18 |
| It takes a beating during a beer bash | 37 |
| It takes a beating | 18 |
| It swings in the mouth | 22 |
| It swings between trees | 23 |
| It swims in a fur | 17 |
| It sweeps across the face | 25 |
| It swallowed Amittai's son: Jonah 1:17 | 42 |
| It survived the crashing rocks, in myth | 39 |
| It surrounds the Vatican | 24 |
| It surrounds the puzzles' long answers | 42 |
| It surrounds the pupil | 22 |
| It surrounds the Parthenon | 26 |
| It surrounds the Isle of Man | 28 |
| It surrounds St.-Pierre | 23 |
| It surrounds San Marino | 23 |
| It surrounds Paros | 18 |
| It surrounds Lesotho: Abbr. | 27 |
| It surrounds Lesotho | 20 |
| It surrounds Città del Vaticano | 34 |
| It surrounds a pit | 18 |
| It surrounds a lens | 19 |
| It surrounds a house | 20 |
| It supports women | 17 |
| It supports the spinal column | 29 |
| It supports the cast | 20 |
| It supports spectacles | 22 |
| It supports 32 "men" | 30 |
| It supplies drivers | 19 |
| It summons doctors prematurely? | 31 |
| It suits you | 12 |
| It suggests the vowel pattern in the five starred answers | 57 |
| It suggests a response | 22 |
| It sucks | 8 |
| It succeeded "Let It Be" as Billboard's #1 single | 63 |
| It sublimes at -109.26°F | 27 |
| It struck F.D.R. in 1921 | 24 |
| It strives underground | 22 |
| It strikes the ball | 19 |
| It stretches from the Atlantic to the Pacific | 45 |
| It stretches from Maine to Florida | 34 |
| It stretches from Iberia to Siberia | 35 |
| It stretches during exercise | 28 |
| It stretches at the gym | 23 |
| It stretches across a tennis court | 34 |
| It stretched from central Mexico to Guatemala | 45 |
| It stores fish in a pouch | 25 |
| It stores data permanently | 26 |
| It stops when it's depressed | 32 |
| It stops traffic | 16 |
| It stops the swinging, briefly | 30 |
| It stops the presses | 20 |
| It stops in the cellar | 22 |
| It stops at Penn Station | 24 |
| It stops at Manhattan's Washington Square and Rockefeller Center | 68 |
| It stops at la estación | 26 |
| It stops at each sta. | 21 |
| It stops a run | 14 |
| It stopped at Truman | 20 |
| It stole a Hearst in '74 [SEE NOTE ABOVE] | 45 |
| It stocks lox | 13 |
| It stocks blocks | 16 |
| It stirs things up | 18 |
| It stinks | 9 |
| It stings | 9 |
| It stimulates the immune system | 31 |
| It stimulates a sense | 21 |
| It sticks to your hair | 22 |
| It sticks to the windshield | 27 |
| It sticks to the ribs | 21 |
| It sticks out of a scabbard | 27 |
| It sticks out of a rowboat | 26 |
| It sticks out in some joints | 28 |
| It sticks out at the side | 25 |
| It sticks in your throat | 24 |
| It sticks in the kitchen | 24 |
| It sticks and bonds | 19 |
| It steers a mushing team | 24 |
| It steadies the ship | 20 |
| It stays the same for astronauts, even when they lose weight | 60 |
| It stays the same | 17 |