| Sign of foreboding | 18 |
| Sign of fitness | 15 |
| Sign of fitful sleep | 20 |
| Sign of fish | 12 |
| Sign of fiscal fitness? | 23 |
| Sign of fire | 12 |
| Sign of financial woe? | 22 |
| Sign of feline felicity | 23 |
| Sign of fear | 12 |
| Sign of fatigue | 15 |
| Sign of family leadership, maybe | 32 |
| Sign of fallibility | 19 |
| Sign of fall | 12 |
| Sign of error | 13 |
| Sign of ennui | 13 |
| Sign of engine trouble, perhaps | 31 |
| Sign of engine trouble | 22 |
| Sign of emptiness | 17 |
| Sign of embarrassment? | 22 |
| Sign of embarrassment | 21 |
| Sign of eloquence | 17 |
| Sign of economic upswing | 24 |
| Sign of eccentricity? | 21 |
| Sign of early August | 20 |
| Sign of drainage | 16 |
| Sign of disuse | 14 |
| Sign of distress, perhaps | 25 |
| Sign of distress, in plants | 27 |
| Sign of distress | 16 |
| Sign of dissent | 15 |
| Sign of disrespect | 18 |
| Sign of displeasure | 19 |
| Sign of disgrace | 16 |
| Sign of disapproval | 19 |
| Sign of deterioration | 21 |
| Sign of desperation | 19 |
| Sign of derision | 16 |
| Sign of decay | 13 |
| Sign of debt | 12 |
| Sign of danger | 14 |
| Sign of damage | 14 |
| Sign of culture | 15 |
| Sign of coryza | 14 |
| Sign of corrosion | 17 |
| Sign of correction | 18 |
| Sign of controversy | 19 |
| Sign of contentment | 19 |
| Sign of contempt | 16 |
| Sign of condensation | 20 |
| Sign of conceit | 15 |
| Sign of coming danger | 21 |
| Sign of cold feet? | 18 |
| Sign of class | 13 |
| Sign of childish displeasure | 28 |
| Sign of change at the Vatican | 29 |
| Sign of change | 14 |
| Sign of caution | 15 |
| Sign of burnout hidden in eight puzzle answers | 46 |
| Sign of burnout | 15 |
| Sign of browning | 16 |
| Sign of Broadway success | 24 |
| Sign of boredom | 15 |
| Sign of bipolar disorder | 24 |
| Sign of being a non-native speaker | 34 |
| Sign of balance | 15 |
| Sign of bad weather | 19 |
| Sign of bad reception | 21 |
| Sign of availability | 20 |
| Sign of autumn's beginning | 30 |
| Sign of autumn | 14 |
| Sign of auto body aging | 23 |
| Sign of authority | 17 |
| Sign of August | 14 |
| Sign of audience approval | 25 |
| Sign of assent | 14 |
| Sign of Aries | 13 |
| Sign of April Fool's Day? | 29 |
| Sign of approval | 16 |
| Sign of appreciation | 20 |
| Sign of apathy | 14 |
| Sign of anger | 13 |
| Sign of an untreated pool | 25 |
| Sign of an overflow | 19 |
| Sign of an old injury | 21 |
| Sign of an injury | 17 |
| Sign of an indifferent homemaker | 32 |
| Sign of an escape? | 18 |
| Sign of an escape, perhaps | 26 |
| Sign of an error | 16 |
| Sign of an engine problem | 25 |
| Sign of an economic upswing | 27 |
| Sign of an approaching storm | 28 |
| Sign of an allergy | 18 |
| Sign of an absent mind | 22 |
| Sign of amusement | 17 |
| Sign of alien life, some say | 28 |
| Sign of agreement | 17 |
| Sign of aging? | 14 |
| Sign of aging | 13 |
| Sign of age? | 12 |