| October Revolution leader | 25 |
| October social occasion | 23 |
| October victory for Yale | 24 |
| October's birthstone | 24 |
| October's gemstone | 22 |
| Octogenarian mag mogul | 22 |
| Octogenarian's decade | 25 |
| Octogenarian's goal | 23 |
| Octogenarian's trait | 24 |
| Octopus costume features | 24 |
| Octopus in a Disney film | 24 |
| Octopus on Muppets shows | 24 |
| Octopus tentacle count | 22 |
| Octopus' abundance | 22 |
| Octopus's relative | 22 |
| Ocular cleansing receptacle | 27 |
| Ocular fluid or wet wit? | 24 |
| Ocular signs of planning? | 25 |
| Oculist's interest | 22 |
| Oculist's specialty | 23 |
| Odalisque's quarters | 24 |
| Odalisque's residence | 25 |
| Odalisques' places | 22 |
| Odd and even, at times | 22 |
| Odd character on your lawn | 26 |
| Odd container for troubles? | 27 |
| Odd couple or dead ends? | 24 |
| Odd Future release, e.g. | 24 |
| Odd in an unsettling way | 24 |
| Odd man with two couples | 24 |
| Odd name of classic TV | 22 |
| Odd or even, in roulette | 24 |
| Odd or strange in nature | 24 |
| Odd place for a cradle | 22 |
| Odd thing to find in a dryer | 28 |
| Odd way to check for ore? | 25 |
| Odd ___ (rap collective) | 24 |
| Odd, as a range of knowledge | 28 |
| Odd-numbered page, often | 24 |
| Odd-shaped reef denizen | 23 |
| Oddballs may draw them | 22 |
| Oddities of a polecat? | 22 |
| Oddjob's creator, Fleming | 29 |
| Oddly-shaped game birds? | 24 |
| Odds and ends abbreviation | 26 |
| Odds and ends for sale | 22 |
| Odds and ends of fabrics | 24 |
| Odds and ends, in business | 26 |
| Odds of being one: 1 in 83 | 26 |
| Odds-and-ends abbreviation | 26 |
| Odds-and-ends category | 22 |
| Odds-and-ends storage areas | 27 |
| Odds-taker's assent | 23 |
| Oddsmaker's concern | 23 |
| Oddsmaker's equalizer | 25 |
| Oddsmaker's figure | 22 |
| Oddsmaker's last words? | 27 |
| Oddsmaker's nightmare | 25 |
| Odessa residents, e.g. | 22 |
| Odessa-to-Waco direction | 24 |
| Odets's 1935 stage hit | 26 |
| Odets, this was your sting! | 27 |
| Odette's daytime form | 25 |
| Odie's original owner | 25 |
| Odilon ___, French painter | 26 |
| Odin's bellicose son | 24 |
| Odin's belligerent son | 26 |
| Odin's eight-legged mount | 29 |
| Odin's spouse: Var. | 23 |
| Odin's thunderous son | 25 |
| Odin's worshippers | 22 |
| Odin, Thor, Balder et al. | 25 |
| Odist to a nightingale | 22 |
| Odist's contraction | 23 |
| Odist's deep black | 22 |
| Odist's inspiration | 23 |
| Odist's preposition | 23 |
| Odists' instruments | 23 |
| Odo portrayer Auberjonois | 25 |
| Odom of the L.A. Clippers | 25 |
| Odom of the LA Clippers | 23 |
| Odomes of the Buffalo Bills | 27 |
| Odometer readout in a new car | 29 |
| Odontologist's org. | 23 |
| Odor fighter from Clorox | 24 |
| ODs, with "out" | 25 |
| Odysseus trio, to Homer | 23 |
| Odysseus' faithful dog | 26 |
| Odysseus' homeland | 22 |
| Odysseus' hometown | 22 |
| Odysseus' life saver | 24 |
| Odysseus' narrator | 22 |
| Odysseus' one-eyed jailer | 29 |
| Odysseus' smart dog | 23 |
| Odysseus' temptresses | 25 |
| Odysseus's adviser | 22 |
| Odysseus's advisor | 22 |
| Odysseus's faithful dog | 27 |
| Odysseus, to Polyphemus | 23 |
| Odyssey with Kirk and Spock | 27 |