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Answer:
SIGEP
Possible Questions:
Popular fraternity, familiarly
Member of a popular college frat
Largest frat in the U.S.
Largest college fraternity in the U.S., in brief
Frat. whose alumni include Dr. Seuss and John Goodman
First college frat to charter a chapter in all 50 states
College frat with the greatest number of chapter houses (200+)
Coll. fraternity with a skull-and-crossbones symbol