Possible Questions:
- Bother
- Nuisance
- Hurt
- Stitch
- Annoyance
- Distress
- Big bother
- Grief
- Misery
- Suffering
- Discomfort
- Aspirin target
- Ache
- Anguish
- Pest
- Travail
- Liniment target
- Tylenol target
- Analgesic target
- Agony
- French bread
- Hassle
- Charley horse, e.g.
- Suffering partner?
- Prerequisite for gain?
- Ibuprofen target
- Botheration
- Bratty kid
- Bothersome person
- Analgesic's target
- Pill
- Aleve target
- Advil target
- Suffering partner
- Partner of suffering
- No gain without it
- Major nuisance
- Annoying sort
- "No ___, no gain"
- ___ in the neck
- Major inconvenience
- Major hassle
- It hurts
- Irksome sort
- Cause of a wince
- Bread, in Brest
- Bothersome task
- Bodily distress
- Aggrieve
- __ in the neck (pest)
- Unpleasant sensation
- Troublesome one
- This may stab or shoot
- There's no gain without it
- Suffering's partner, in court
- Stitch, e.g.
- Royal annoyance
- Prerequisite for a weightlifter's gain?
- Physical suffering
- Ouch inducer
- Joy's antithesis
- Endorphins producer
- Emotional distress
- Cause to grimace
- Anodyne's target
- "Sweet is pleasure after ___": Dryden
- Young brother, often
- World of hurt
- What lines with stars at the end indicate in comics
- What dols measure
- What an analgesic stops
- What a French baker produces
- What a dolorimeter measures
- That hurts
- T-___ (noted Auto-Tune user)
- Strong discomfort
- Some athletes play through it
- Sibling, at times?
- Result of punishment
- Requisite for gain, so they say
- Reliever's target
- Reason to take acetaminophen
- Reason for a clinic visit
- Proverbial problem for the neck or butt
- Pesky one
- Percocet's target
- Ouch's cause
- Number's target?
- Nuisance, so to speak
- Nice bread
- Neuralgia
- Neck affliction
- Little brother, at times
- It might be in the neck
- It may be unbearable
- It can follow a fall
- It can be chronic or shooting
- It "clings cruelly to us," according to Keats
- Hardly pleasure
- Grimace inducer
- Gagne ___ (French breadwinner)
- Feeling that makes you say "Ow!"
- Excedrin target
- Clubber Lang's prediction for Rocky
- Clinton felt yours
- Bread, in Bruxelles
- Bread, in Bayonne
- Bread in Brest
- Baby brother, often
- Arduous chore
- Ache's cousin
- "Royal" nuisance
- "Royal" annoyance
- "Our Lady of ___": Swinburne
- "No __, no gain"
- "No ___, no gain" (gym saying)
- "I feel your __"
- ___ in the ass