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Answer:
OPIUM
Possible Questions:
Poppy product
Kind of pipe
Kind of den
Poppy drug
Hookah substance
Addictive narcotic
Painkiller
Codeine source
Poppy derivative
Drug from poppies
Den drug
Yves St. Laurent fragrance
Poppy-based narcotic
Drug served in a den
Soporific substance
Poppy yield
Poppy narcotic
Poe's drug of choice
Narcotic from poppies
Narcotic from a poppy
It's addictive
Heroin source
Drug in a den
Yves Saint Laurent fragrance
YSL fragrance
What De Quincey ate
Vice of Dorian Gray
Subject of Great Britain/China wars
Southeast Asia product
Source of codeine
Smuggler's stock
Smuggled stuff
Sherlock Holmes's drug
Religion, to Karl Marx
Poppy extract
Perfume from YSL
Painkiller since ancient times
Narcotic collected by scraping seedpods
It might be smoked in a den
It may be found in a den
Heroin is made from it
Drug that's smoked in a pipe
Drug that may be taken in tea
Drug once smoked in dens
Drug made from poppies
Drug in the den?
Drug at the center of some 19th-century wars
Dried poppy juice
Dope in a den?
De Quincey subject
Coleridge's drug of choice
Cause of an 1839-42 war
Cause of 19th century warfare between England and China
"Confessions of an English ___-Eater"
___ Wars (conflicts of the 19th century)
___ War: 1839–42
__ den